Drug-membrane interactions: significance for medicinal chemistry

M Lucio, J Lima, S Reis - Current medicinal chemistry, 2010 - ingentaconnect.com
Generally drugs can act on the level of different biological membranes as well as inside the
cells that are limited by membranes. Even in the latter situation, drugs must still interact with …

Interaction of nonsteroidal anti-inflammatory drugs with membranes: in vitro assessment and relevance for their biological actions

C Pereira-Leite, C Nunes, S Reis - Progress in lipid research, 2013 - Elsevier
Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most commonly used drugs
in the world due to their anti-inflammatory, analgesic and antipyretic properties …

Membrane fusion induced by small molecules and ions

S Mondal Roy, M Sarkar - Journal of lipids, 2011 - Wiley Online Library
Membrane fusion is a key event in many biological processes. These processes are
controlled by various fusogenic agents of which proteins and peptides from the principal …

A molecular biophysical approach to diclofenac topical gastrointestinal damage

E Fernandes, TB Soares, H Gonçalves… - International journal of …, 2018 - mdpi.com
Diclofenac (DCF), the most widely consumed non-steroidal anti-inflammatory drug (NSAID)
worldwide, is associated with adverse typical effects, including gastrointestinal (GI) …

Piroxicam, a traditional non-steroidal anti-inflammatory drug (NSAID) causes apoptosis by ROS mediated Akt activation

N Rai, M Sarkar, S Raha - Pharmacological Reports, 2015 - Springer
Abstract Background Piroxicam (Px) belongs to the oxicam group of the non-steroidal anti-
inflammatory drugs (NSAIDs) and have been shown to exert chemopreventive and …

Imidacloprid impedes mitochondrial function and induces oxidative stress in cotton bollworm, Helicoverpa armigera larvae (Hubner: Noctuidae)

B Nareshkumar, SM Akbar, HC Sharma… - Journal of bioenergetics …, 2018 - Springer
Neonicotinoids have high agonistic affinity to insect nicotinic acetylcholine receptors
(nAChR) and are frequently used as insecticides against most devastating lepidopteran …

Influence of eugenol on the organization and dynamics of lipid membranes: a phase-dependent study

G Meher, H Chakraborty - Langmuir, 2018 - ACS Publications
Eugenol is known for its antimicrobial effects against microorganisms responsible for
infectious diseases in humans, food-borne pathogens, and oral pathogens. In spite of …

Flavonol clustering in model lipid membranes: DSC, AFM, force spectroscopy and MD simulations study

A Sadžak, Z Brkljača, I Crnolatac, G Baranović… - Colloids and Surfaces B …, 2020 - Elsevier
We here report on flavonols (myricetin (MCE) and its glycoside myricitrin (MCI))–1, 2-
dimyristoyl-sn-glycero-3-phosphocholine (DMPC) membrane interactions focusing on the …

Membrane fusion: a new function of non steroidal anti-inflammatory drugs

H Chakraborty, S Mondal, M Sarkar - Biophysical Chemistry, 2008 - Elsevier
Membrane fusion is an important event in many biological processes and is characterized
by several intermediate steps of which content mixing between the two fusing vesicles …

Non-steroidal anti-inflammatory drug induced membrane fusion: concentration and temperature effects

S Mondal, M Sarkar - The Journal of Physical Chemistry B, 2009 - ACS Publications
Membrane fusion is a critical step in many biological events. The fusion process is always
induced by different fusogenic agents of which proteins and peptides form the largest group …