Apicomplexans form a large phylum of parasitic protists, some of which cause severe
diseases in humans. Most notorious is Plasmodium, the agent of malaria, which kills around …

Toxoplasma (toxoplasmosis) and Plasmodium (malaria) use unique secretory organelles for
migration, cell invasion, manipulation of host cell functions, and cell egress. In particular, the …

This 2e of Toxoplasma gondii reflects the significant advances in the field in the last 5 years,
including new information on the genomics, epigenomics and proteomics of T. gondii as well …

Apicomplexan parasites cause persistent mortality and morbidity worldwide through
diseases including malaria, toxoplasmosis, and cryptosporidiosis. Ca 2+ signaling pathways …

The Toxoplasma inner membrane complex (IMC) is a unique organelle that plays critical
roles in parasite motility, invasion, egress, and replication. The IMC is delineated into the …

The phylum Apicomplexa comprises a group of obligate intracellular parasites of broad
medical and agricultural significance, including Toxoplasma gondii and the malaria-causing …

Apicomplexa are intracellular parasites that cause important human diseases including
malaria and toxoplasmosis. During host cell infection new parasites are formed through a …

Fundamental processes that govern the lytic cycle of the intracellular parasite Toxoplasma
gondii are regulated by several signalling pathways. However, how these pathways are …

Apicomplexan parasites use Ca 2+-regulated exocytosis to secrete essential virulence
factors from specialized organelles called micronemes. Ca 2+-dependent protein kinases …

Toxoplasma gondii resides in its intracellular niche by employing a series of specialized
secretory organelles that play roles in invasion, host cell manipulation, and parasite …