Polyurethane is an excellent and widely used polymer material. In synthesizing
polyurethane, the structure of soft and hard segments in polyurethane could be adjusted …

Biomaterials are mostly any natural and synthetic materials which are compatible from a
biological point of view with the human body. Biomaterials are widely used to sustain …

The current clinical solutions, including mechanical and bioprosthetic valves for valvular
heart diseases, are plagued by coagulation, calcification, nondurability, and the inability to …

Conventional synthesis routes for thermoplastic polyurethanes (TPUs) still require the use of
isocyanates and tin-based catalysts, which pose considerable safety and environmental …

Polyurethanes (PUs) are among the most studied, manufactured, and employed polymers
thanks to their versatility and wide range of applications. However, their synthesis generally …

Transcatheter aortic valve replacement (TAVR) has the advantages of less trauma and faster
postoperative recovery, which has brought the possibility to the elderly patient with valvular …

Heart valve leaflet substrates with native trilayer and anisotropic structures are crucial for
successful heart valve tissue engineering. In this study, we used the electrospinning …

Bioactive hydrogel coatings offer a promising route to introduce sustained
thromboresistance to cardiovascular devices without compromising bulk mechanical …

Cardiovascular disease (CVD) remains the leading cause of mortality worldwide. In
particular, patients who suffer from ischemic heart disease (IHD) that is not amenable to …

Device failure due to undesired biological responses remains a substantial roadblock in the
development and translation of new devices into clinical care. Polyethylene glycol (PEG) …