Targeting endothelial cell-specific molecule 1 protein in cancer: a promising therapeutic approach

H Zhang, YW Shen, LJ Zhang, JJ Chen, HT Bian… - Frontiers in …, 2021 - frontiersin.org
Despite the dramatic advances in cancer research in the past few years, effective
therapeutic strategies are urgently needed. Endothelial cell-specific molecule 1 (ESM-1), a …

Tobacco smoking and survival after a prostate cancer diagnosis: A systematic review and meta-analysis

E Darcey, T Boyle - Cancer Treatment Reviews, 2018 - Elsevier
Background While a number of studies indicate tobacco smoking has a detrimental impact
on survival and recurrence after a prostate cancer diagnosis, there has been no quantitative …

Clinical potential of circulating tumor cells in colorectal cancer: a prospective study

DH Baek, GH Kim, G Am Song, IS Han… - Clinical and …, 2019 - journals.lww.com
OBJECTIVES: Circulating tumor cells (CTCs) in the blood have been used as diagnostic
markers in patients with colorectal cancer (CRC). In this study, we evaluated a CTC …

Proteoglycan Endocan: A multifaceted therapeutic target in Cancer

KF Pan, YC Yang, WJ Lee, KT Hua… - Biochimica et Biophysica …, 2022 - Elsevier
Endocan is known to be a circulating dermatan sulfate proteoglycan that regulates
endothelial cell function. Dysregulation of endocan expression is observed not only in the …

Diagnostic and prognostic value of serum endocan levels in patients with COVID-19

S Görgün, Ş Cindoruk, E Özgen, M Yadigaroğlu… - …, 2021 - journals.sagepub.com
We aimed to evaluate whether there was a relationship between endocan (human
endothelial cell-specific molecule-1) levels and disease prognosis in patients who …

ESM-1: a novel tumor biomaker and its research advances

C Li, H Geng, L Ji, X Ma, Q Yin… - Anti-Cancer Agents in …, 2019 - ingentaconnect.com
Background: Cancer kills nearly 9,000,000 people worldwide, and its mortality was reported
up to 28% in the past decade. Few available tumor markers have been known to help early …

Endocan: A novel biomarker of endothelial dysfunction in depression?

E Şahan, EM Güler, A Tangılntız, İ Kırpınar - Journal of Psychiatric …, 2023 - Elsevier
Endocan is a proteoglycan secreted from endothelium upon endothelial damage. Since
depression is associated with higher inflammation and oxidative stress to the vascular …

The Potential of Extracellular Matrix-and Integrin Adhesion Complex-Related Molecules for Prostate Cancer Biomarker Discovery

I Samaržija - Biomedicines, 2023 - mdpi.com
Prostate cancer is among the top five cancer types according to incidence and mortality. One
of the main obstacles in prostate cancer management is the inability to foresee its course …

Is the plasma endocan level a reliable predictor for the severity of erectile dysfunction?

Ö Onuk, B Arslan, TC Gezmis, B Çetin, T Göv… - … Urology and Nephrology, 2018 - Springer
Purpose The aim of our study was to assess the correlation between serum endocan level
and erectile dysfunction (ED). Methods A total of 92 patients were reviewed in this study after …

Endocan in Acute Leukemia: Current Knowledge and Future Perspectives

H Reikvam, KJ Hatfield, Ø Wendelbo, R Lindås… - Biomolecules, 2022 - mdpi.com
Endocan is a soluble dermatan sulfate proteoglycan expressed by endothelial cells and
detected in serum/plasma. Its expression is increased in tumors/tumor vessels in several …