Tissue engineering is promising to meet the increasing need for bone regeneration.
Nanostructured calcium phosphate (CaP) biomaterials/scaffolds are of special interest as …

For decades, scientists have been using two-dimensional cell culture platforms for high-
throughput drug screening of anticancer drugs. Growing evidence indicates that the results …

Surface topography impacts on cell growth and differentiation, but it is not trivial to generate
defined surface structures and to assess the relevance of specific topographic parameters …

Advances in additive manufacturing have led to diverse patient‐specific implant designs
utilizing computed tomography, but this requires intensive work and financial implications …

During embryogenesis and tissue maintenance and repair in an adult organism, a myriad of
stem cells are regulated by their surrounding extracellular matrix (ECM) enriched with …

Chemical, mechanical, and topographic extracellular matrix (ECM) cues have been
extensively studied for their influence on cell behavior. These ECM cues alter cell adhesion …

Nanostructured titanium implants are recognized for inducing osteogenesis, but the cell
signal transductions related to topography are not fully understood. Implant topography is …

Vascularization is a fundamental prerequisite for large bone construct development and
remains one of the main challenges of bone tissue engineering. Our current study presents …

Electrosprayed microspheres for bone regeneration are conventionally restricted by the lack
of osteogenic modulation for both encapsulated stem cells and surrounding cells at the …

Cell-derived matrices (CDMs) are an interesting alternative to conventional sources of
extracellular matrices (ECMs) as CDMs mimic the natural ECM composition better and are …