Innovations to culturing the uncultured microbial majority

WH Lewis, G Tahon, P Geesink, DZ Sousa… - Nature Reviews …, 2021 - nature.com
Despite the surge of microbial genome data, experimental testing is important to confirm
inferences about the cell biology, ecological roles and evolution of microorganisms. As the …

Revision of the 'Candidatus Phytoplasma' species description guidelines

A Bertaccini, Y Arocha-Rosete… - … of Systematic and …, 2022 - microbiologyresearch.org
The genus 'Candidatus Phytoplasma'was proposed to accommodate cell wall-less bacteria
that are molecularly and biochemically incompletely characterized, and colonize plant …

RESCRIPt: Reproducible sequence taxonomy reference database management

MS Robeson, DR O'Rourke, BD Kaehler… - PLoS computational …, 2021 - journals.plos.org
Nucleotide sequence and taxonomy reference databases are critical resources for
widespread applications including marker-gene and metagenome sequencing for …

Proposal to reclassify the proteobacterial classes Deltaproteobacteria and Oligoflexia, and the phylum Thermodesulfobacteria into four phyla reflecting major …

DW Waite, M Chuvochina, C Pelikan… - … of Systematic and …, 2020 - microbiologyresearch.org
The class Deltaproteobacteria comprises an ecologically and metabolically diverse group of
bacteria best known for dissimilatory sulphate reduction and predatory behaviour. Although …

MiDAS 4: A global catalogue of full-length 16S rRNA gene sequences and taxonomy for studies of bacterial communities in wastewater treatment plants

MKD Dueholm, M Nierychlo, KS Andersen… - Nature …, 2022 - nature.com
Microbial communities are responsible for biological wastewater treatment, but our
knowledge of their diversity and function is still poor. Here, we sequence more than 5 million …

Evaluation of 16S rRNA gene sequencing for species and strain-level microbiome analysis

JS Johnson, DJ Spakowicz, BY Hong… - Nature …, 2019 - nature.com
The 16S rRNA gene has been a mainstay of sequence-based bacterial analysis for
decades. However, high-throughput sequencing of the full gene has only recently become a …

Metagenomic and metabolomic analyses reveal distinct stage-specific phenotypes of the gut microbiota in colorectal cancer

S Yachida, S Mizutani, H Shiroma, S Shiba… - Nature medicine, 2019 - nature.com
In most cases of sporadic colorectal cancers, tumorigenesis is a multistep process, involving
genomic alterations in parallel with morphologic changes. In addition, accumulating …

Promising bioactive compounds from the marine environment and their potential effects on various diseases

A Karthikeyan, A Joseph, BG Nair - Journal of Genetic Engineering and …, 2022 - Elsevier
Background The marine environment hosts a wide variety of species that have evolved to
live in harsh and challenging conditions. Marine organisms are the focus of interest due to …

GABA-modulating bacteria of the human gut microbiota

P Strandwitz, KH Kim, D Terekhova, JK Liu… - Nature …, 2019 - nature.com
The gut microbiota affects many important host functions, including the immune response
and the nervous system. However, while substantial progress has been made in growing …

Analysis of 1,000+ Type-Strain Genomes Substantially Improves Taxonomic Classification of Alphaproteobacteria

A Hördt, MG López, JP Meier-Kolthoff… - Frontiers in …, 2020 - frontiersin.org
The class Alphaproteobacteria is comprised of a diverse assemblage of Gram-negative
bacteria that includes organisms of varying morphologies, physiologies and habitat …