Macrophage defense mechanisms against intracellular bacteria

G Weiss, UE Schaible - Immunological reviews, 2015 - Wiley Online Library
Macrophages and neutrophils play a decisive role in host responses to intracellular bacteria
including the agent of tuberculosis (TB), M ycobacterium tuberculosis as they represent the …

Molecular basis of mycobacterial survival in macrophages

JA Awuh, TH Flo - Cellular and Molecular Life Sciences, 2017 - Springer
Macrophages play an essential role in the immune system by ingesting and degrading
invading pathogens, initiating an inflammatory response and instructing adaptive immune …

Acquired immunodeficiencies and tuberculosis: focus on HIV/AIDS and diabetes mellitus

K Ronacher, SA Joosten, R van Crevel… - Immunological …, 2015 - Wiley Online Library
The spread of human immunodeficiency virus (HIV) infection within Africa led to marked
increases in numbers of cases of tuberculosis (TB), and although the epidemic peaked in …

[HTML][HTML] Cathelicidin: Insights into Its Impact on Metabolic Syndrome and Chronic Inflammation

AD Popa, A Gherasim, L Caba, O Niță, M Graur… - Metabolites, 2024 - mdpi.com
Background/Objectives: LL-37 is associated with metabolic syndrome (MetS), a constellation
of risk factors comprising obesity, insulin resistance (IR), dyslipidemia, and hypertension …

Functions of antimicrobial peptides in vertebrates

E Edilia Avila - Current Protein and Peptide Science, 2017 - ingentaconnect.com
Objective: The aim of this review is to examine the multiple activities of antimicrobial
peptides (AMPs) in vertebrates. Content: The largest AMP families are the cathelicidins and …

Diabetes mellitus as hub for tuberculosis infection: A snapshot

R Pal, MA Ansari, S Hameed… - International journal of …, 2016 - Wiley Online Library
Tuberculosis (TB) still remains the thorn in the flesh of efficient therapeutics affecting one‐
third of global population annually. There are several factors that enhance the susceptibility …

Dietary modulation of endogenous host defense peptide synthesis as an alternative approach to in-feed antibiotics

K Robinson, X Ma, Y Liu, S Qiao, Y Hou, G Zhang - Animal Nutrition, 2018 - Elsevier
Traditionally, antibiotics are included in animal feed at subtherapeutic levels for growth
promotion and disease prevention. However, recent links between in-feed antibiotics and a …

The microbiome at the pulmonary alveolar niche and its role in Mycobacterium tuberculosis infection

AJ Adami, JL Cervantes - Tuberculosis, 2015 - Elsevier
Advances in next generation sequencing (NGS) technology have provided the tools to
comprehensively and accurately characterize the microbial community in the respiratory …

The microbiota of human lung of pulmonary tuberculosis and the alteration caused by anti-tuberculosis drugs

M Zhang, L Shen, X Zhou, H Chen - Current Microbiology, 2022 - Springer
An in-depth understanding of the lung microbiota in tuberculosis (TB) infection could provide
optimal strategies for the prophylaxis, diagnosis, and treatment of the disease. Only a few …

Expansive vascular remodeling and increased vascular calcification response to cholecalciferol in a murine model of obesity and insulin resistance

LS Carmo, EA Burdmann, MR Fessel… - … , and vascular biology, 2019 - Am Heart Assoc
Objective—We hypothesized that ob/ob mice develop expansive vascular remodeling
associated with calcification. Approach and Results—We quantified and investigated …