Nucleobase modifications are prevalent in eukaryotic mRNA and their discovery has
resulted in the emergence of epitranscriptomics as a research field. The most abundant …

Abstract N 6-Methyladenosine (m6A) is one of the most abundant modifications of the
epitranscriptome and is found in cellular RNAs across all kingdoms of life. Advances in …

Over decades, researchers have focused on the epigenetic control of DNA-templated
processes. Histone modification, DNA methylation, chromatin remodeling, RNA modification …

RNA modifications have become hot topics recently. By influencing RNA processes,
including generation, transportation, function, and metabolization, they act as critical …

Over the past decade, mRNA modifications have emerged as important regulators of gene
expression control in cells. Fueled in large part by the development of tools for detecting …

Transfer RNAs (tRNAs) play a central role in protein translation. Studying them has been
difficult in part because a simple method to simultaneously quantify their abundance and …

Following its transcription, RNA can be modified by> 170 chemically distinct types of
modifications—the epitranscriptome. In recent years, there have been substantial efforts to …

Specific chemical modifications of biological molecules are an efficient way of regulating
molecular function, and a plethora of downstream signalling pathways are influenced by the …

Background The epigenetic regulation of immune response has been demonstrated in
recent studies. Nonetheless, potential roles of RNA N6-methyladenosine (m 6 A) …

Hepatocellular carcinoma (HCC) accounts for the majority of primary liver cancers and is
characterized by high recurrence and heterogeneity, yet its mechanism is not well …