Regulation and functions of non-m6A mRNA modifications

H Sun, K Li, C Liu, C Yi - Nature Reviews Molecular Cell Biology, 2023 - nature.com
Nucleobase modifications are prevalent in eukaryotic mRNA and their discovery has
resulted in the emergence of epitranscriptomics as a research field. The most abundant …

A new phase of networking: the molecular composition and regulatory dynamics of mammalian stress granules

SR Millar, JQ Huang, KJ Schreiber, YC Tsai… - Chemical …, 2023 - ACS Publications
Stress granules (SGs) are cytosolic biomolecular condensates that form in response to
cellular stress. Weak, multivalent interactions between their protein and RNA constituents …

The integral role of RNA in stress granule formation and function

D Campos-Melo, ZCE Hawley… - Frontiers in Cell and …, 2021 - frontiersin.org
Stress granules (SGs) are phase-separated, membraneless, cytoplasmic ribonucleoprotein
(RNP) assemblies whose primary function is to promote cell survival by condensing …

RNA methylations in human cancers

X Han, M Wang, YL Zhao, Y Yang, YG Yang - Seminars in cancer biology, 2021 - Elsevier
RNA methylations, as the prevalent post-transcriptional modifications, are critical in
regulating various biological processes, such as RNA transcription, splicing, structure …

Composition and function of stress granules and P-bodies in plants

A Kearly, ADL Nelson, A Skirycz… - Seminars in cell & …, 2024 - Elsevier
Abstract Stress Granules (SGs) and Processing-bodies (P-bodies) are biomolecular
condensates formed in the cell with the highly conserved purpose of maintaining balance …

Roles of RNA modifications in diverse cellular functions

E Wilkinson, YH Cui, YY He - Frontiers in Cell and Developmental …, 2022 - frontiersin.org
Chemical modifications of RNA molecules regulate both RNA metabolism and fate. The
deposition and function of these modifications are mediated by the actions of writer, reader …

[图书][B] RNA, the epicenter of genetic information

J Mattick, P Amaral - 2023 - library.oapen.org
The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …

An m6A/m5C/m1A/m7G-related long non-coding RNA signature to predict prognosis and immune features of glioma

D Shao, Y Li, J Wu, B Zhang, S Xie, X Zheng… - Frontiers in …, 2022 - frontiersin.org
Background: Gliomas are the most common and fatal malignant type of tumor of the central
nervous system. RNA post-transcriptional modifications, as a frontier and hotspot in the field …

Epitranscriptomic mRNA modifications governing plant stress responses: underlying mechanism and potential application

J Hu, J Cai, T Xu, H Kang - Plant biotechnology journal, 2022 - Wiley Online Library
Plants inevitably encounter environmental adversities, including abiotic and biotic stresses,
which significantly impede plant growth and reduce crop yield. Thus, fine‐tuning the fate and …

RNA-driven phase transitions in biomolecular condensates

GM Wadsworth, S Srinivasan, LB Lai, M Datta… - Molecular Cell, 2024 - cell.com
RNAs and RNA-binding proteins can undergo spontaneous or active condensation into
phase-separated liquid-like droplets. These condensates are cellular hubs for various …