Guidelines for the use of flow cytometry and cell sorting in immunological studies

A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2021 - Wiley Online Library
The third edition of Flow Cytometry Guidelines provides the key aspects to consider when
performing flow cytometry experiments and includes comprehensive sections describing …

Cellular origin of human B-cell lymphomas

R Küppers, ULF Klein, ML Hansmann… - New England Journal …, 1999 - Mass Medical Soc
The origin of human lymphomas has been studied by various approaches, including
histology and immunophenotyping. In some types of lymphoma these studies suggested the …

Guidelines for the use of flow cytometry and cell sorting in immunological studies

A Cossarizza, HD Chang, A Radbruch… - European journal of …, 2019 - Wiley Online Library
These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …

Clonogenic multiple myeloma progenitors, stem cell properties, and drug resistance

W Matsui, Q Wang, JP Barber, S Brennan, BD Smith… - Cancer research, 2008 - AACR
Many agents are active in multiple myeloma, but the majority of patients relapse. This clinical
pattern suggests most cancer cells are eliminated, but cells with the clonogenic potential to …

Multiple myeloma: increasing evidence for a multistep transformation process

M Hallek, P Leif Bergsagel… - Blood, The Journal of …, 1998 - ashpublications.org
MULTIPLE MYELOMA (MM) is a clonal B-cell neo-plasm that affects terminally differentiated
B cells (ie, plasma cells) and may proceed through different phases: an inactive phase in …

Chromosome translocations in multiple myeloma

PL Bergsagel, WM Kuehl - Oncogene, 2001 - nature.com
Multiple myeloma (MM), a malignant tumor of somatically mutated, isotype-switched plasma
cells (PC), usually arises from a common benign PC tumor called Monoclonal Gammopathy …

Clonal immunoglobulin against lysolipids in the origin of myeloma

S Nair, AR Branagan, J Liu… - … England Journal of …, 2016 - Mass Medical Soc
Antigen-driven selection has been implicated in the pathogenesis of monoclonal
gammopathies. Patients with Gaucher's disease have an increased risk of monoclonal …

Pathogenesis of myeloma

KC Anderson, RD Carrasco - Annual Review of Pathology …, 2011 - annualreviews.org
Multiple myeloma (MM) is a neoplasm of post–germinal center, terminally differentiated B
cells. It is characterized by a multifocal proliferation of clonal, long-lived plasma cells within …

In multiple myeloma, t (4; 14)(p16; q32) is an adverse prognostic factor irrespective of FGFR3 expression

JJ Keats, T Reiman, CA Maxwell… - Blood, The Journal …, 2003 - ashpublications.org
This study analyzed the frequency and clinical significance of t (4; 14)(p16; q32) in multiple
myeloma (MM) among 208 patients with MM and 52 patients with monoclonal gammopathy …

[HTML][HTML] Interleukin-6 in human multiple myeloma

B Klein, XG Zhang, ZY Lu, R Bataille - Blood, 1995 - Elsevier
WITHIN THE LAST 5 YEARS, two major findings have advanced our knowledge of the
biology of human multiple myeloma (MM). First, somatic mutations without intraclonal …