Selecting the optimal immunotherapy regimen in driver-negative metastatic NSCLC

MJ Grant, RS Herbst, SB Goldberg - Nature reviews Clinical oncology, 2021 - nature.com
The treatment landscape of driver-negative non-small-cell lung cancer (NSCLC) is rapidly
evolving. Immune-checkpoint inhibitors, specifically those targeting PD-1 or PD-L1, have …

Immunotherapy and liver transplantation: A narrative review of basic and clinical data

CH Wassmer, S El Hajji, X Papazarkadas… - Cancers, 2023 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) represents one of the main indications
for liver transplantation. Over recent years, immune checkpoint inhibitor (ICI) therapy has …

[HTML][HTML] Immune checkpoint blockade for organ-transplant recipients with cancer: a review

A Rünger, D Schadendorf, A Hauschild… - European Journal of …, 2022 - Elsevier
Clinical trials studying immune checkpoint inhibitors (ICIs) have excluded
immunocompromised patients, and little is known about the safety and efficacy of …

[HTML][HTML] Immune checkpoint inhibitors and kidney toxicity: advances in diagnosis and management

H Seethapathy, SM Herrmann, ME Sise - Kidney Medicine, 2021 - Elsevier
Immune checkpoint inhibitors are now approved for more than 50 indications, and
increasing numbers of patients with advanced cancer are receiving immunotherapy …

Immune checkpoint inhibitors in malignancies after liver transplantation: A systematic review and pooled analysis

S Kayali, A Pasta, MC Plaz Torres, A Jaffe… - Liver …, 2023 - Wiley Online Library
Background and aims Treatment of de novo malignancies and recurrent hepatocellular
carcinoma with immune checkpoint inhibitors (ICI) in liver transplant recipients (LT) is an …

Pretransplant use of immune checkpoint inhibitors for hepatocellular carcinoma: A multicenter, retrospective cohort study

Z Guo, Y Liu, Q Ling, L Xu, T Wang, J Zhu, Y Lin… - American Journal of …, 2024 - Elsevier
Immune checkpoint inhibitors (ICIs) as a downstaging or bridging therapy for liver
transplantation (LT) in hepatocellular carcinoma patients are rapidly increasing. However …

[HTML][HTML] Immunotherapy use outside clinical trial populations: never say never?

K Rzeniewicz, J Larkin, AM Menzies, S Turajlic - Annals of Oncology, 2021 - Elsevier
Background Based on favourable outcomes in clinical trials, immune checkpoint inhibitors
(ICIs), most notably programmed cell death protein 1 (PD-1) and cytotoxic T-lymphocyte …

De novo malignancy after liver transplantation: risk assessment, prevention, and management—Guidelines From the ILTS-SETH Consensus Conference

J Colmenero, P Tabrizian, P Bhangui, DJ Pinato… - …, 2022 - journals.lww.com
De novo malignancies (DNMs) following liver transplantation (LT) have been reported as 1
of the major causes of late mortality, being the most common cause of death in the second …

[HTML][HTML] Understanding immune perspectives and options for the use of checkpoint immunotherapy in HCC post liver transplant

CM Anugwom, TM Leventhal, JD Debes - Hepatoma research, 2022 - ncbi.nlm.nih.gov
Abstract Treatment modalities for hepatocellular carcinoma (HCC) vary from surgical
techniques and interventional radiologic strategies to systemic therapy. For the latter, the …

[HTML][HTML] Immune checkpoint inhibitor therapy for malignant tumors in liver transplantation recipients: A systematic review of the literature

P Zhang, G Zhu, L Li, G Lai, Z Wang, C Sun, W Xia… - Transplantation …, 2022 - Elsevier
Background Treatment for de novo or recurrent tumors of liver transplantation (LT) recipients
is challenging and immune checkpoint inhibitor (ICI) is recently well developed and could be …