Step-by-step fabrication of heart-on-chip systems as models for cardiac disease modeling and drug screening
Cardiovascular diseases are caused by hereditary factors, environmental conditions, and
medication-related issues. On the other hand, the cardiotoxicity of drugs should be …
medication-related issues. On the other hand, the cardiotoxicity of drugs should be …
Smart contact lenses—A step towards non-invasive continuous eye health monitoring
According to the age-old adage, while eyes are often considered the gateway to the soul,
they might also provide insights into a more pragmatic aspect of our health: blood sugar …
they might also provide insights into a more pragmatic aspect of our health: blood sugar …
[HTML][HTML] Automated fabrication of a scalable heart-on-a-chip device by 3D printing of thermoplastic elastomer nanocomposite and hot embossing
The successful translation of organ-on-a-chip devices requires the development of an
automated workflow for device fabrication, which is challenged by the need for precise …
automated workflow for device fabrication, which is challenged by the need for precise …
Heart‐on‐a‐Chip Model of Epicardial–Myocardial Interaction in Ischemia Reperfusion Injury
Epicardial cells (EPIs) form the outer layer of the heart and play an important role in
development and disease. Current heart‐on‐a‐chip platforms still do not fully mimic the …
development and disease. Current heart‐on‐a‐chip platforms still do not fully mimic the …
Advances in cardiac tissue engineering and heart‐on‐a‐chip
Recent advances in both cardiac tissue engineering and hearts‐on‐a‐chip are grounded in
new biomaterial development as well as the employment of innovative fabrication …
new biomaterial development as well as the employment of innovative fabrication …
SARS-CoV-2 pathogenesis in an angiotensin II–induced heart-on-a-chip disease model and extracellular vesicle screening
Adverse cardiac outcomes in COVID-19 patients, particularly those with preexisting cardiac
disease, motivate the development of human cell-based organ-on-a-chip models to …
disease, motivate the development of human cell-based organ-on-a-chip models to …
Emergent trends in organ-on-a-chip applications for investigating metastasis within tumor microenvironment: A comprehensive bibliometric analysis
C He, F Lu, Y Liu, Y Lei, X Wang, N Tang - Heliyon, 2024 - cell.com
Background With the burgeoning advancements in disease modeling, drug development,
and precision medicine, organ-on-a-chip has risen to the forefront of biomedical research …
and precision medicine, organ-on-a-chip has risen to the forefront of biomedical research …
Biofabrication strategies for cardiac tissue engineering
Highlights•Biofabrication enables creation of cardiac tissue for drug testing and
implantation.•3D printing provides unique solution for tissue vascularization.•Translational …
implantation.•3D printing provides unique solution for tissue vascularization.•Translational …
Integrating organoids and organ-on-a-chip devices
Organoids and organs-on-chips are two rapidly emerging 3D cell culture techniques that
aim to bridge the gap between in vitro 2D cultures and animal models to enable clinically …
aim to bridge the gap between in vitro 2D cultures and animal models to enable clinically …
Biohybrid printing approaches for cardiac pathophysiological studies
Bioengineered hearts, which include single cardiomyocytes, engineered heart tissue, and
chamber-like models, generate various biosignals, such as contractility …
chamber-like models, generate various biosignals, such as contractility …