Over the years, seaweeds have been highlighted as valuable natural sources of bioactive
polysaccharides. Fucoidan, a sulphated polysaccharide mainly from brown seaweeds …

1.1. General Considerations Structural intricacies of carbohydrate molecules and their
propensity to form varied linkages, substitutions, and branching patterns have fascinated …

Summary Programmed cell death 1 (PD-1) is highly expressed on exhausted T cells and
inhibits T cell activation. Antibodies that block the interaction between PD-1 and its ligand …

Fucosylation is one of the most common modifications involving oligosaccharides on
glycoproteins or glycolipids. Fucosylation comprises the attachment of a fucose residue to N …

Metastatic colorectal cancer (mCRC) is a major cause of cancer-related mortality due to the
absence of effective therapeutics. Thus, it is urgent to discover new drugs for mCRC …

The key role played by fucose in glycoprotein and cellular function has prompted significant
research toward identifying recombinant and biochemical strategies for blocking its …

In recent years, the use of lectins for screening of potential biomarkers has gained increased
importance in cancer research, given the development in glycobiology that highlights altered …

Highlights•The structure of more than 26 fungal lectins has been described recently.•Binding
to non-self glycans results in toxicity towards predators.•Structural details from pathogenic …

Glycosylation is one of the most significant post-translational modifications occurring to
proteins, since it affects some of their basic properties, such as their half-life or biological …

In 2007, 1179 papers were published that involved the application of optical biosensors.
Reported developments in instrument hardware, assay design, and immobilization …