The emergence of phase separation as an organizing principle in bacteria

CA Azaldegui, AG Vecchiarelli, JS Biteen - Biophysical journal, 2021 - cell.com
Recent investigations in bacteria suggest that membraneless organelles play a crucial role
in the subcellular organization of bacterial cells. However, the biochemical functions and …

Determinants of bacterial morphology: from fundamentals to possibilities for antimicrobial targeting

MCF van Teeseling, MA de Pedro, F Cava - Frontiers in microbiology, 2017 - frontiersin.org
Bacterial morphology is extremely diverse. Specific shapes are the consequence of adaptive
pressures optimizing bacterial fitness. Shape affects critical biological functions, including …

How do bacteria localize proteins to the cell pole?

G Laloux, C Jacobs-Wagner - Journal of cell science, 2014 - journals.biologists.com
It is now well appreciated that bacterial cells are highly organized, which is far from the initial
concept that they are merely bags of randomly distributed macromolecules and chemicals …

Getting in the Loop: Regulation of Development in Caulobacter crescentus

PD Curtis, YV Brun - Microbiology and Molecular Biology Reviews, 2010 - Am Soc Microbiol
Caulobacter crescentus is an aquatic Gram-negative alphaproteobacterium that undergoes
multiple changes in cell shape, organelle production, subcellular distribution of proteins, and …

LadS is a calcium-responsive kinase that induces acute-to-chronic virulence switch in Pseudomonas aeruginosa

UN Broder, T Jaeger, U Jenal - Nature microbiology, 2016 - nature.com
Virulence of pathogenic bacteria is a tightly controlled process to facilitate invasion and
survival in host tissues. Although pathways controlling virulence have been defined in detail …

A multidomain hub anchors the chromosome segregation and chemotactic machinery to the bacterial pole

Y Yamaichi, R Bruckner, S Ringgaard… - Genes & …, 2012 - genesdev.cshlp.org
The cell poles constitute key subcellular domains that are often critical for motility,
chemotaxis, and chromosome segregation in rod-shaped bacteria. However, in nearly all …

The diversity and evolution of cell cycle regulation in alpha-proteobacteria: a comparative genomic analysis

M Brilli, M Fondi, R Fani, A Mengoni, L Ferri… - BMC systems …, 2010 - Springer
Abstract Background In the bacterium Caulobacter crescentus, CtrA coordinates DNA
replication, cell division, and polar morphogenesis and is considered the cell cycle master …

The Global Regulatory Architecture of Transcription during the Caulobacter Cell Cycle

B Zhou, JM Schrader, VS Kalogeraki, E Abeliuk… - PLoS …, 2015 - journals.plos.org
Each Caulobacter cell cycle involves differentiation and an asymmetric cell division driven
by a cyclical regulatory circuit comprised of four transcription factors (TFs) and a DNA …

Phase separation modulates the assembly and dynamics of a polarity-related scaffold-signaling hub

W Tan, S Cheng, Y Li, XY Li, N Lu, J Sun… - Nature …, 2022 - nature.com
Asymmetric cell division (ACD) produces morphologically and behaviorally distinct cells and
is the primary way to generate cell diversity. In the model bacterium Caulobacter crescentus …

Alternative mechanism for bacteriophage adsorption to the motile bacterium Caulobacter crescentus

RC Guerrero-Ferreira, PH Viollier… - Proceedings of the …, 2011 - National Acad Sciences
2D and 3D cryo-electron microscopy, together with adsorption kinetics assays of ϕCb13 and
ϕCbK phage-infected Caulobacter crescentus, provides insight into the mechanisms of …