Herein, we review mechanisms regulating cerebral blood flow (CBF), with specific focus on
humans. We revisit important concepts from the older literature and describe the interaction …

Visual impairment intracranial pressure (VIIP) syndrome is considered an unexplained
major risk for future long-duration spaceflight. NASA recently redefined this syndrome as …

Current protocols examining cerebral autoregulation (CA) parameters require participants to
refrain from exercise for 12–24 hr, however there is sparse objective evidence examining …

Many astronauts experience ocular structural and functional changes during long‐duration
spaceflight, including choroidal folds, optic disc edema, globe flattening, optic nerve sheath …

Cerebrovascular reactivity and cerebral autoregulation are two major mechanisms that
regulate cerebral blood flow. Both mechanisms are typically assessed in either supine or …

Alterations in cerebral hemodynamics in microgravity are hypothesized to occur during
spaceflight and could be linked to the Visual Impairment and Intracranial Pressure …

It is well known that exposure to microgravity in astronauts leads to a plethora physiological
responses such as headward fluid shift, body unloading, and cardiovascular deconditioning …

This review focuses on the effects of different body positions on intracranial fluid dynamics,
including cerebral arterial and venous flow, cerebrospinal fluid (CSF) hydrodynamics, and …

Cerebral autoregulation (CA) is a key mechanism to protect the brain against excessive
fluctuations in blood pressure (BP) and maintain cerebral blood flow. Analyzing the …

Cerebral autoregulation (CA) is thought to maintain relatively constant cerebral blood flow
(CBF) across normal blood pressures. To determine if postural changes alter CA, we …