Proteomics defines plasma biomarkers for the early diagnosis of biliary atresia

M Fu, Z Guo, Y Chen, JR Lamb, S Zhong… - Journal of Proteome …, 2024 - ACS Publications
Early diagnosis of biliary atresia (BA) is crucial for improving the chances of survival and
preserving the liver function of pediatric patients with BA. Herein, we performed proteomics …

[HTML][HTML] Polymeric immunoglobulin receptor promotes Th2 immune response in the liver by increasing cholangiocytes derived IL-33: a diagnostic and therapeutic …

Y Li, TY Li, Q Qiao, MT Zhang, MX Tong, LF Xu… - …, 2024 - thelancet.com
Background Biliary atresia (BA) is a devastating neonatal cholangiopathy with an unclear
pathogenesis, and prompt diagnosis of BA is currently challenging. Methods Proteomic and …

Increased serum GM-CSF at diagnosis of biliary atresia is associated with improved biliary drainage

SA Taylor, S Harpavat, KD Gromer, V Andreev… - Pediatric …, 2025 - nature.com
Background The immune heterogeneity of biliary atresia (BA) presents a challenge for
development of prognostic biomarkers. This study aimed to identify early immune signatures …

Time-course analysis of liver and serum galectin-3 in acute liver injury after alpha-galactosylceramide injection

M Matsuo, A Kanbe, K Noguchi, A Niwa, Y Imaizumi… - Plos one, 2024 - journals.plos.org
Galectin-3 is a beta-galactoside-binding lectin that plays important roles in diverse
physiological functions, such as cell proliferation, apoptosis, and mRNA splicing. This …

Evaluating serum galectin-3 binding protein as a diagnostic and prognostic biomarker in pulmonary arterial hypertension: a comparative study

A Albulushi, LS Alfehaid, M Alhussein… - Global …, 2024 - globalcardiology.info
Background: Pulmonary arterial hypertension (PAH) is a severe condition with poor
prognosis, characterized by elevated pulmonary artery pressure that leads to right …