The “basal ganglia” refers to a group of subcortical nuclei responsible primarily for motor
control, as well as other roles such as motor learning, executive functions and behaviors …

The midbrain dopamine (mDA) system is composed of molecularly and functionally distinct
neuron subtypes that mediate specific behaviours and are linked to various brain diseases …

Parkinson's disease is characterized by abundant α-synuclein (α-Syn) neuronal inclusions,
known as Lewy bodies and Lewy neurites, and the massive loss of midbrain dopamine …

We found that optogenetic burst stimulation of hippocampal dopaminergic fibers from
midbrain neurons in mice exploring novel environments enhanced the reactivation of …

Midbrain dopamine (mDA) neurons constitute a heterogenous group of cells that have been
intensely studied, not least because their degeneration causes major symptoms in …

Effective approaches to neuropsychiatric disorders require detailed understanding of the
cellular composition and circuitry of the complex mammalian brain. Here, we present a …

Numerous disorders of the central nervous system (CNS) are attributed to the selective
death of distinct neuronal cell populations. Interestingly, in many of these conditions, a …

Auxilin participates in the uncoating of clathrin-coated vesicles (CCVs), thereby facilitating
synaptic vesicle (SV) regeneration at presynaptic sites. Auxilin (DNAJC6/PARK19) loss-of …

Midbrain dopaminergic neurons are essential for appropriate voluntary movement, as
epitomized by the cardinal motor impairments arising in Parkinson's disease. Understanding …

Parkinson's disease (PD) is a neurodegenerative disorder characterized by selective loss of
dopaminergic neurons in the substantia nigra pars compacta (SNpc) region of the midbrain …