The neurodevelopmental and dopamine hypotheses are leading theories of the
pathoetiology of schizophrenia, but they were developed in isolation. However, since they …

Introduction: Electrophysiological (EEG) abnormalities in subjects with schizophrenia have
been largely reported. In the last decades, research has shifted to the identification of …

The brain is a predictive machine. Converging data suggests a diametric predictive strategy
from autism spectrum disorders (ASD) to schizophrenic spectrum disorders (SSD). Whereas …

Converging evidence implicates redox dysregulation as a pathological mechanism driving
the emergence of psychosis. Increased oxidative damage and decreased capacity of …

Psychotic disorders affect 3% of the population at some stage in life, are a leading cause of
disability, and impose a great economic burden on society. Major breakthroughs in the …

Mothers exposed to infections during pregnancy disproportionally birth children who
develop autism and schizophrenia, disorders associated with altered GABAergic function …

New treatment development for psychiatric disorders depends critically upon the
development of physiological measures that can accurately translate between preclinical …

Objective: Brain oscillations play a pivotal role in synchronizing responses of local and
global ensembles of neurons. Patients with schizophrenia exhibit impairments in oscillatory …

Neurexins are presynaptic transmembrane proteins crucial for synapse development and
organization. Deletion and missense mutations in all three Neurexin genes have been …

Abstract Purpose of Review Current research is examining predictors of the transition to
psychosis in youth who are at clinical high risk based on attenuated psychotic symptoms …