Insights into endothelial progenitor cells: origin, classification, potentials, and prospects

H Chopra, MK Hung, DL Kwong… - Stem cells …, 2018 - Wiley Online Library
With the discovery of endothelial progenitor cells (EPCs) in the late 1990s, a paradigm shift
in the concept of neoangiogenesis occurred. The identification of circulating EPCs in …

Autonomic-immune-vascular interaction: an emerging concept for neurogenic hypertension

J Zubcevic, H Waki, MK Raizada, JFR Paton - Hypertension, 2011 - Am Heart Assoc
Hypertension is the single most important risk factor for cardiovascular disease and, thus,
remains a global public health challenge. Significant progress has been made during the …

Altered inflammatory response is associated with an impaired autonomic input to the bone marrow in the spontaneously hypertensive rat

J Zubcevic, JY Jun, S Kim, PD Perez, A Afzal… - …, 2014 - Am Heart Assoc
Autonomic nervous system dysfunction, exaggerated inflammation, and impaired vascular
repair are all hallmarks of hypertension. Considering that bone marrow (BM) is a major …

Endothelial progenitor cells for diagnosis and prognosis in cardiovascular disease

CO Aragona, E Imbalzano, F Mamone… - Stem cells …, 2016 - Wiley Online Library
Objective. To identify, evaluate, and synthesize evidence on the predictive power of
circulating endothelial progenitor cells (EPCs) in cardiovascular disease, through a …

Endothelial progenitor cells dysfunctions and cardiometabolic disorders: from mechanisms to therapeutic approaches

AC Peyter, JB Armengaud, E Guillot… - International Journal of …, 2021 - mdpi.com
Metabolic syndrome (MetS) is a cluster of several disorders, such as hypertension, central
obesity, dyslipidemia, hyperglycemia, insulin resistance and non-alcoholic fatty liver …

Circulating endothelial progenitor cells as biomarkers for prediction of cardiovascular outcomes

C Bakogiannis, D Tousoulis… - Current medicinal …, 2012 - ingentaconnect.com
Experimental studies suggest that bone marrow-derived endothelial progenitor cells (EPCs)
play an important role in the maintenance of endothelial integrity and hemostasis. The …

Carvacrol improves vascular function in hypertensive animals by modulating endothelial progenitor cells

TAF Gonçalves, VS Lima, AJPO de Almeida… - Nutrients, 2023 - mdpi.com
Carvacrol, a phenolic monoterpene, has diverse biological activities, highlighting its
antioxidant and antihypertensive capacity. However, there is little evidence demonstrating its …

Endothelial progenitor cells and hypertension: current concepts and future implications

S Luo, W Xia, C Chen, EA Robinson, J Tao - Clinical Science, 2016 - portlandpress.com
The discovery of endothelial progenitor cells (EPCs), a group of cells that play important
roles in angiogenesis and the maintenance of vascular endothelial integrity, has led to …

Body mass index contributes to sympathovagal imbalance in prehypertensives

GK Pal, A Chandrasekaran, AP Hariharan… - BMC Cardiovascular …, 2012 - Springer
Background The present study was conducted to assess the nature of sympathovagal
imbalance (SVI) in prehypertensives by short-term analysis of heart rate variability (HRV) to …

Brain-mediated dysregulation of the bone marrow activity in angiotensin II–induced hypertension

JY Jun, J Zubcevic, Y Qi, A Afzal, JM Carvajal… - …, 2012 - Am Heart Assoc
Oxidative stress in the brain is implicated in increased sympathetic drive, inflammatory
status, and vascular dysfunctions, associated with development and establishment of …