[HTML][HTML] Challenges for immunotherapy for the treatment of platinum resistant ovarian cancer
O Le Saux, I Ray-Coquard, SI Labidi-Galy - Seminars in cancer biology, 2021 - Elsevier
Platinum resistant ovarian cancer, usually defined as progression occurring within 6 months
after completing platinum-based therapy, is a heterogeneous disease with poor prognosis …
after completing platinum-based therapy, is a heterogeneous disease with poor prognosis …
Hippo signaling in the ovary: emerging roles in development, fertility, and disease
Emerging studies indicate that the Hippo pathway, a highly conserved pathway that
regulates organ size control, plays an important role in governing ovarian physiology …
regulates organ size control, plays an important role in governing ovarian physiology …
Neutrophil extracellular traps: a new player in cancer metastasis and therapeutic target
D Yang, J Liu - Journal of Experimental & Clinical Cancer Research, 2021 - Springer
Abstract Neutrophil Extracellular Traps (NETs) are neutrophil-derived extracellular scaffolds,
which typically consist of fibrous decondensed chromatins decorated with histones and …
which typically consist of fibrous decondensed chromatins decorated with histones and …
FOXM1: a multifunctional oncoprotein and emerging therapeutic target in ovarian cancer
Simple Summary Ovarian cancer is a lethal disease in women with a 10-year survival rate
of< 40% worldwide. A key molecular alteration in ovarian cancer is the aberrant …
of< 40% worldwide. A key molecular alteration in ovarian cancer is the aberrant …
Synthesis of quercetin functionalized wurtzite type zinc oxide nanoparticles and their potential to regulate intrinsic apoptosis signaling pathway in human metastatic …
V Ramalingam, PM Sathya, T Srivalli, H Mohan - Life Sciences, 2022 - Elsevier
In the present study, the wurtzite (WZ) type of zinc oxide (ZnO) nanoparticles were
synthesized and functionalized with quercetin (ZnO@ Quercetin) for the treatment of ovarian …
synthesized and functionalized with quercetin (ZnO@ Quercetin) for the treatment of ovarian …
Insights into the role of oxidative stress in ovarian cancer
DN Ding, LZ Xie, Y Shen, J Li, Y Guo… - Oxidative medicine …, 2021 - Wiley Online Library
Oxidative stress (OS) arises when the body is subjected to harmful endogenous or
exogenous factors that overwhelm the antioxidant system. There is increasing evidence that …
exogenous factors that overwhelm the antioxidant system. There is increasing evidence that …
Untargeted metabolomics analysis on kidney tissues from mice reveals potential hypoxia biomarkers
Chronic hypoxia may have a huge impact on the cardiovascular and renal systems.
Advancements in microscopy, metabolomics, and bioinformatics provide opportunities to …
Advancements in microscopy, metabolomics, and bioinformatics provide opportunities to …
TRAIL-dependent apoptosis of peritoneal mesothelial cells by NK cells promotes ovarian cancer invasion
AM Steitz, C Schröder, I Knuth, CU Keber… - Iscience, 2023 - cell.com
A crucial requirement for metastasis formation in ovarian high-grade serous carcinoma
(HGSC) is the disruption of the protective peritoneal mesothelium. Using co-culture systems …
(HGSC) is the disruption of the protective peritoneal mesothelium. Using co-culture systems …
L1CAM is required for early dissemination of fallopian tube carcinoma precursors to the ovary
Most ovarian high-grade serous carcinomas (HGSC) arise from Serous Tubal Intraepithelial
Carcinoma (STIC) lesions in the distal end of the fallopian tube (FT). Formation of STIC …
Carcinoma (STIC) lesions in the distal end of the fallopian tube (FT). Formation of STIC …
Cellular models of development of ovarian high‐grade serous carcinoma: A review of cell of origin and mechanisms of carcinogenesis
High‐grade serous carcinoma (HGSC) is the most common and malignant histological type
of epithelial ovarian cancer, the origin of which remains controversial. Currently, the …
of epithelial ovarian cancer, the origin of which remains controversial. Currently, the …