The benefits of polyclonal antibodies as tools for assay-specific target discovery and
detection are numerous. As the future of basic research, diagnostics and biomarker …

The selection of an appropriate therapy and dosing regimen is a significant challenge in the
treatment of cancer. Although there are recommended standardized chemotherapy …

Biopharmaceuticals directed against tumor necrosis factor-alpha, integrins, interleukins,
interferons and their receptors have become key agents for the management of inflammatory …

In this study, we developed a simple liquid chromatography-tandem mass spectrometry (LC-
MS/MS) assay to quantify trastuzumab in human serum using aptamers for sample …

Therapeutic antibodies are increasingly used to treat various diseases, including neoplasms
and chronic inflammatory diseases. Antibodies exhibit complex pharmacokinetic properties …

Background: This study compared the performance of plasma infliximab and adalimumab
quantification using a commercially available kit (mAbXmise kit) and mass spectrometry …

In solid organ transplantation (SOT), biologicals such as recombinant therapeutic proteins,
monoclonal antibodies, fusion proteins and conjugates are increasingly used for …

The promising pipeline of therapeutic monoclonal antibodies (mAbs) demands robust
bioanalytical methods with swift development times for pharmacokinetic studies. Over the …

We report on the development of a versatile and accurate bioanalytical method for
bevacizumab using a pretreatment method combining affinity purification with anti-idiotypic …

The treatment of rheumatoid arthritis (RA) has largely improved in the biopharmaceutical
era. These compounds, primarily tumor necrosis factor (TNF) inhibitors, are effective, but …