Intervertebral disc (IVD) degeneration (IDD), a highly prevalent pathological condition
worldwide, is widely associated with back pain. Treatments available compensate for the …

Regenerative medicine for intervertebral disc (IVD) disease, by utilizing chondrocytes, IVD
cells, and stem cells, has progressed to clinical trials in the treatment of back pain, and has …

Intervertebral disc degeneration is thought to be a major contributor to low back pain, the
etiology of which is complex and not yet fully understood. To compensate for the lack of drug …

Tissue engineering is a promising approach for the repair and regeneration of cartilaginous
tissue. Appropriate three-dimensional scaffolding materials that mimic cartilage are ideal for …

An important mechanism for the development of intervertebral disc degeneration (IDD) is an
imbalance between anti-inflammatory and pro-inflammatory cytokines. Therapeutic and non …

Intervertebral disc degeneration (IDD), characterized by conversion of genotypic and
phenotypic, is a major etiology of low back pain and disability. In general, this process starts …

Background Intervertebral disc (IVD) shows aging and degenerative changes earlier than
any other body connective tissue. Its repair and regeneration provide a considerable …

Intervertebral disc degeneration is the main cause of low back pain. Traditional treatment
methods cannot repair degenerated intervertebral disc tissue. The emergence of stem cell …

Chondropathies are increasing worldwide, but effective treatments are currently lacking.
Mesenchymal stromal cell (MSCs) transplantation represents a promising approach to …

Background: Stem cells (SCs) therapy for intervertebral disc degeneration (IDD) has been
studied for nearly 20 years and it is an important part of regenerative medicine and tissue …