Detection of toxic small molecule contaminants with sensitivity, accuracy, and specificity is a
challenging task. Traditionally used HPLC and mass spectrometry-based assays suffer from …

Background In the context of the current pandemic caused by the novel coronavirus,
molecular detection is not limited to the clinical laboratory, but also faces the challenge of …

The pandemic due to the outbreak of 2019 coronavirus disease (COVID-19) caused by
novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has raised significant …

Infectious pathogens cause severe human illnesses and great deaths per year worldwide.
Rapid, sensitive, and accurate detection of pathogens is of great importance for preventing …

It is of great significance to develop consensus, easy-to-use and conceptually new methods
for guaranteeing food safety. CRISPR/Cas system is an emerging technology with excellent …

Clustered, regularly interspaced short palindromic repeats (CRISPR)-based diagnoses,
derived from gene-editing technology, have been exploited for less than 5 years and are …

Escherichia coli O157: H7 is a major cause of fresh vegetable-associated infections that can
threaten human health. A method for rapidly detecting food-borne pathogens should be …

Background Agri-food safety has been considered as one of the most important public
concerns worldwide. From farm to table, food crops and foods are extremely vulnerable to …

Food safety problems have become one of the most important public health issues
worldwide. Therefore, the development of rapid, effective and robust detection is of great …

Abstract In this study, Lba Cas12a (Cpf1) as one of the CRISPR systems from
Lachnospiraceae bacterium was coupled with a hybridization chain reaction (HCR) to …