The proper transfer of genetic information from DNA to RNA to protein is essential for cell-
fate control, development, and health. Methylation of DNA, RNAs, histones, and non-histone …

Brain metastases (BMs) are the most common and among the deadliest brain tumors.
Currently, there are no reliable predictors of BM development from primary cancer, which …

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) constitutes a rare and aggressive
malignancy originating from plasmacytoid dendritic cells (pDCs) with a primarily cutaneous …

Liquid biopsy has been gradually applied to the clinical diagnosis and treatment of tumors
because of its non-invasive and real-time reflection of the tumor status, as well as the …

Triple-negative breast cancers (TNBC) include diverse carcinomas with heterogeneous
clinical behavior. DNA methylation is a useful tool in classifying a variety of cancers. In this …

Purpose. To establish an effective and accurate prognostic nomogram for lung
adenocarcinoma (LUAD). Patients and Methods. 62,355 LUAD patients from 1975 to 2016 …

Group of Genetics and Epigenetics, de Duve Institute, Université catholique de Louvain,
Brussels, Belgium Correspondence to: Charles De Smet. de Duve Institute, 75 Avenue …

Pleural mesothelioma (PM) is a rare and aggressive cancer type, typically diagnosed at
advanced stages. Distinguishing PM from other lung diseases is often challenging. There is …

Lower-grade gliomas (LGGs) exhibit highly variable clinical behaviors, while classic
histology characteristics cannot accurately reflect the authentic biological behaviors, clinical …

Background Lung adenocarcinoma (LUAD) is a heterogeneous tumor characterized by
diverse genetic and molecular alterations. Developing a multi-omics-based classification …