Antimicrobial resistance (AMR) is emerging as the next potential pandemic. Different
microorganisms, including the bacteria Acinetobacter baumannii, Clostridioides difficile …

The glycocalyx, a thick layer of carbohydrates, surrounds the cell wall of most bacterial and
parasitic pathogens. Recognition of these unique glycans by the human immune system …

Streptococcus pneumoniae (the pneumococcus) is an important human pathogen. Its
virulence is largely due to its polysaccharide capsule, which shields it from the host immune …

Marine secondary metabolites are a promising source of unexploited drugs that have a wide
structural diversity and have shown a variety of biological activities. These compounds are …

Introduction: Glycoconjugate vaccines are among the safest and most efficacious vaccines
developed during the last 30 years. They are a potent tool for prevention of life-threatening …

Glycoconjugate vaccines obtained by chemical linkage of a carbohydrate antigen to a
protein are part of routine vaccinations in many countries. Licensed antimicrobial glycan …

Primary examples in vaccine design have shown good levels of carbohydrate-specific
antibody generation when raised using extracted or fully synthetic capsular polysaccharide …

Carbohydrate antigens have shown promise as important targets for developing effective
vaccines and pathogen detection strategies. Modifying purified microbial glycans through …

Aims: Coupling of capsular polysaccharides of pathogens to immunogenic protein carriers
(conjugate vaccines) improves carbohydrate immune response. Our idea is to explore gold …

The development and use of antibacterial glycoconjugate vaccines have significantly
reduced the occurrence of potentially fatal childhood and adult diseases such as …