3+ 7 Combined chemotherapy for acute myeloid leukemia: is it time to say goodbye?

K Tang, AC Schuh, KWL Yee - Current Oncology Reports, 2021 - Springer
Abstract Purpose of Review With the recent approval of multiple new drugs for the treatment
of acute myeloid leukemia (AML), the relevance of conventional treatment approaches, such …

[HTML][HTML] Real-world experience with CPX-351 in high-risk acute myeloid leukemia

RM Lemoli, P Montesinos, A Jain - Critical reviews in oncology/hematology, 2023 - Elsevier
Abstract CPX-351, a dual-drug liposomal encapsulation of daunorubicin/cytarabine, was
approved for newly diagnosed therapy-related acute myeloid leukemia (AML) and AML with …

Lower-intensity CPX-351 plus venetoclax induction for adults with newly diagnosed AML unfit for intensive chemotherapy

GL Uy, V Pullarkat, P Baratam, RK Stuart… - Blood …, 2024 - ashpublications.org
Preclinical data suggest a rationale for combining CPX-351, a dual-drug liposomal
encapsulation of daunorubicin and cytarabine, with venetoclax, a B-cell lymphoma-2 …

Management of Acute Myeloid Leukemia with Myelodysplasia-Related Changes and Therapy-Related Acute Myeloid Leukemia

JP Bewersdorf, AM Zeidan - Pathogenesis and Treatment of Leukemia, 2023 - Springer
Acute myeloid leukemia with myelodysplasia-related changes (AML-MRC) and therapy-
related AML (t-AML) are often combined under the term secondary AML (sAML) and are …

Whom should we treat with novel agents? Specific indications for specific and challenging populations

L Wilde, M Kasner - Hematology, 2021 - ashpublications.org
A relative wealth of new therapies for acute myeloid leukemia (AML) have led to a rapid shift
in treatment paradigms for this disease. Understanding whom, when, and how to treat is …

Current status of CPX-351 therapy in acute myeloid leukemia and myelodysplastic syndrome

S Alotaibi, D Niederwieser, SO Ahmed, J Sanz… - … Myeloma and Leukemia, 2022 - Elsevier
Acute myeloid leukemia (AML) treatment landscape had evolved over the last decades with
better understanding of the disease genomics and the use of the targeted therapy, despite …