The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
caused a devastating pandemic. Although most people infected with SARS-CoV-2 develop …

Biosensors and nanoscale analytical tools have shown huge growth in literature in the past
20 years, with a large number of reports on the topic of 'ultrasensitive','cost-effective', and …

A central paradigm of immunity is that interferon (IFN)-mediated antiviral responses precede
pro-inflammatory ones, optimizing host protection and minimizing collateral damage,. Here …

How the innate and adaptive host immune system miscommunicate to worsen COVID-19
immunopathology has not been fully elucidated. Here, we perform single-cell deep-immune …

Viral infections of the lower respiratory tract are a leading cause of mortality. Mounting
evidence indicates that most severe cases are characterized by aberrant immune responses …

Type I and type II interferons (IFN) are central to both combating virus infection and
modulating the antiviral immune response. Indeed, an absence of either the receptor for type …

Acute respiratory distress syndrome (ARDS) caused by SARS-CoV-2 is largely the result of
a dysregulated host response, followed by damage to alveolar cells and lung fibrosis …

The SARS-Cov2 infection triggers a multisystem inflammatory disorder, knowing as COVID-
19, a pandemic disease. This disease is characterized by acute respiratory distress …

Lambda interferons (IFNλs) or type III IFNs share homology, expression patterns, signaling
cascades, and antiviral functions with type I IFNs. This has complicated the unwinding of …

Neutrophils and polymorphonucler myeloid-derived suppressor cells (PMN-MDSC) share
origin and many morphological and phenotypic features. However, they have different …