Prolidase is a ubiquitous enzyme that plays a major role in the metabolism of proline-rich
proteins. Prolidase deficiency is a rare autosomal recessive inborn metabolic and …

Simple Summary Studies of various types of cancers have found proline metabolism to be a
key player in tumor development, involved in basic metabolic pathways, regulating cell …

Background Prolidase deficiency (PD) is an autosomal recessive inborn multisystemic
disease caused by mutations in the PEPD gene encoding the enzyme prolidase D, leading …

Purpose Prolidase deficiency is a rare inborn error of metabolism causing ulcers and other
skin disorders, splenomegaly, developmental delay, and recurrent infections. Most of the …

Prolidase Deficiency (PD) is an autosomal recessive rare disorder caused by loss or
reduction of prolidase enzymatic activity due to variants in the PEPD gene. PD clinical …

Prolidase enzyme, which catalyzes the final step in collagen metabolism can influence the
cognitive functions through changes in extracellular matrix (ECM) resulting in altered …

We investigated the effect of 3-iodothyronamine (T1AM) on thermogenic substrates in brown
adipocytes (BAs). BAs isolated from the stromal fraction of rat brown adipose tissue were …

Objective: Prolidase is an enzyme that releases proline and is vital in extracellular matrix
(ECM) remodeling, fueling white matter dynamics. Serum prolidase activity (SPA) is elevated …

Prolidase deficiency is an ultra-rare metabolic disorder caused by mutations in the PEPD
gene, which causes a wide range of symptoms including chronic ulcers, recurrent infections …

The aim of the present study is to investigate the association of prolidase activity in
streptozotocin (STZ) induced diabetic rat model with hippocampus-dependent spatial …