Cognitive impairment in chronic kidney disease: vascular milieu and the potential therapeutic role of exercise

UG Bronas, H Puzantian… - BioMed research …, 2017 - Wiley Online Library
Chronic kidney disease (CKD) is considered a model of accelerated aging. More
specifically, CKD leads to reduced physical functioning and increased frailty, increased …

Consequences of CKD on functioning

P Kittiskulnam, A Sheshadri, KL Johansen - Seminars in nephrology, 2016 - Elsevier
Chronic kidney disease (CKD) is highly prevalent in the United States and throughout the
world, 1 with approximately 13% of adults affected. 2 In addition, according to recent …

Hemodialysis induces an acute decline in cerebral blood flow in elderly patients

HA Polinder-Bos, DV García, J Kuipers… - Journal of the …, 2018 - journals.lww.com
The initiation of hemodialysis is associated with an accelerated decline of cognitive function
and an increased incidence of cerebrovascular accidents and white matter lesions …

Randomized clinical trial of dialysate cooling and effects on brain white matter

MT Eldehni, A Odudu, CW McIntyre - Journal of the American …, 2015 - journals.lww.com
Hemodialysis is associated with significant circulatory stress that could produce recurrent
and cumulative ischemic insults to multiple organs, such as the brain. We aimed to …

Relationship between hypotension and cerebral ischemia during hemodialysis

C MacEwen, S Sutherland, J Daly, C Pugh… - Journal of the …, 2017 - journals.lww.com
The relationship between BP and downstream ischemia during hemodialysis has not been
characterized. We studied the dynamic relationship between BP, real-time symptoms, and …

Cognitive function and white matter changes associated with renal transplantation

A Gupta, RJ Lepping, ASL Yu, RD Perea… - American journal of …, 2016 - karger.com
Background: End-stage renal disease (ESRD) is a disease with an aging population and a
high prevalence of cognitive impairment affecting quality of life, health care costs and …

Reduced white matter integrity and cognitive deficits in maintenance hemodialysis ESRD patients: a diffusion-tensor study

R Zhang, K Liu, L Yang, T Zhou, S Qian, B Li, Z Peng… - European …, 2015 - Springer
Objectives The purpose of this investigation was to examine the association between
cognition disorders and microstructural white matter (WM) changes in maintenance …

Abnormal degree centrality in neurologically asymptomatic patients with end-stage renal disease: a resting-state fMRI study

S Li, X Ma, R Huang, M Li, J Tian, H Wen, C Lin… - Clinical …, 2016 - Elsevier
Objective End-stage renal disease (ESRD), characterized by multi-organ dysfunction, has
been shown to co-occur with abnormal brain function. Previous resting-state fMRI studies …

Abnormal intrinsic brain activity patterns in patients with end-stage renal disease undergoing peritoneal dialysis: a resting-state functional MR imaging study

S Luo, RF Qi, JQ Wen, JH Zhong, X Kong, X Liang… - Radiology, 2016 - pubs.rsna.org
Purpose To analyze the spontaneous brain activity patterns in patients with end-stage renal
disease (ESRD) undergoing peritoneal dialysis (PD) by using resting-state functional …

Brain white matter microstructure in end‐stage kidney disease, cognitive impairment, and circulatory stress

MT Eldehni, A Odudu… - Hemodialysis International, 2019 - Wiley Online Library
Introduction: Structural and functional brain white matter abnormalities are poorly
characterized in patients with end‐stage kidney disease. Methods: We examined the …