New insights into targeting membrane lipids for cancer therapy

G Preta - Frontiers in cell and developmental biology, 2020 - frontiersin.org
Modulation of membrane lipid composition and organization is currently developing as an
effective therapeutic strategy against a wide range of diseases, including cancer. This field …

The role of structure and biophysical properties in the pleiotropic effects of statins

C Murphy, E Deplazes, CG Cranfield… - International journal of …, 2020 - mdpi.com
Statins are a class of drugs used to lower low-density lipoprotein cholesterol and are
amongst the most prescribed medications worldwide. Most statins work as a competitive …

Effects of statins on the biological features of mesenchymal stem cells and therapeutic implications

AM Gorabi, N Kiaie, M Pirro, V Bianconi… - Heart Failure …, 2021 - Springer
Statins are well-known lipid-lowering drugs. The pleiotropic effects of statins have brought
about some beneficial effects on improving the therapeutic outcomes of cell therapy and …

Application of high resolution NMR (1H and 13C) and FTIR spectroscopy for characterization of light and heavy crude oils

IZ Rakhmatullin, SV Efimov, VA Tyurin… - Journal of Petroleum …, 2018 - Elsevier
High-resolution nuclear magnetic resonance (NMR) and Fourier transform infrared (FTIR)
spectroscopy experiments were applied to obtain detailed information on the hydrocarbon …

The nucleoshuttling of the ATM protein: a unified model to describe the individual response to high-and low-dose of radiation?

E Berthel, N Foray, ML Ferlazzo - Cancers, 2019 - mdpi.com
The evaluation of radiation-induced (RI) risks is of medical, scientific, and societal interest.
However, despite considerable efforts, there is neither consensual mechanistic models nor …

Lipophilic statins inhibit Zika virus production in Vero cells

E Españo, JH Nam, EJ Song, D Song, CK Lee… - Scientific reports, 2019 - nature.com
Zika virus (ZIKV) is a mosquito-borne member of the Flaviviridae family. ZIKV infection has
been associated with neurological complications such as microcephaly in newborns and …

Statin action targets lipid rafts of cell membranes: GIXD/PM-IRRAS investigation of Langmuir monolayers

M Zaborowska, M Broniatowski… - The Journal of …, 2023 - ACS Publications
Lipid rafts are condensed regions of cell membranes rich in cholesterol and sphingomyelin,
which constitute the target for anticholesterolemic drugs-statins. In this work, we use for the …

Qualitative and quantitative analysis of oil samples extracted from some Bashkortostan and Tatarstan oilfields based on NMR spectroscopy data

IZ Rakhmatullin, SV Efimov, BY Margulis… - Journal of Petroleum …, 2017 - Elsevier
Measurements of crude oil samples by nuclear magnetic resonance spectroscopy were
carried out. The quantitative fractions of aromatic molecules and functional groups …

[HTML][HTML] Interaction of statins with phospholipid bilayers studied by solid-state NMR spectroscopy

LF Galiullina, HA Scheidt, D Huster, A Aganov… - … et Biophysica Acta (BBA …, 2019 - Elsevier
Statins are drugs that specifically inhibit the enzyme HMG-CoA reductase and thereby
reduce the concentration of low-density lipoprotein cholesterol, which represents a well …

[HTML][HTML] Interaction of the cholesterol reducing agent simvastatin with zwitterionic DPPC and charged DPPG phospholipid membranes

E Sariisik, M Koçak, FK Baloglu, F Severcan - Biochimica et Biophysica …, 2019 - Elsevier
Simvastatin is a lipid-lowering drug in the pharmaceutical group statins. Interaction of a drug
with lipids may define its role in the system and be critical for its pharmacological activity. We …