Dual relationship between long non-coding RNAs and STAT3 signaling in different cancers: New insight to proliferation and metastasis

M Ashrafizadeh, MH Gholami, S Mirzaei, A Zabolian… - Life sciences, 2021 - Elsevier
Uncontrolled growth and metastasis of cancer cells is an increasing challenge for
overcoming cancer, and improving survival of patients. Complicated signaling networks …

Exploring the roles of lncRNAs in GBM pathophysiology and their therapeutic potential

CT Stackhouse, GY Gillespie, CD Willey - Cells, 2020 - mdpi.com
Glioblastoma (GBM) remains the most devastating primary central nervous system
malignancy with a median survival of around 15 months. The past decades of research have …

Knockdown of lncRNA NEAT1 inhibits Th17/CD4+ T cell differentiation through reducing the STAT3 protein level

X Shui, S Chen, J Lin, J Kong… - Journal of cellular …, 2019 - Wiley Online Library
CD4+ T cells differentiated into Th17 cells are a main cause for occurrence and
development of rheumatoid arthritis (RA). This study aims to define the role of long …

LncRNA CASC9 interacts with CPSF3 to regulate TGF-β signaling in colorectal cancer

K Luo, J Geng, Q Zhang, Y Xu, X Zhou, Z Huang… - Journal of Experimental …, 2019 - Springer
Background Colorectal cancer (CRC) is the third most frequent cancer and the second
leading cause of cancer-related death worldwide. Increasing evidence indicates that the …

[HTML][HTML] LncRNA LINC00689 promotes the growth, metastasis and glycolysis of glioma cells by targeting miR-338-3p/PKM2 axis

X Liu, Q Zhu, Y Guo, Z Xiao, L Hu, Q Xu - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Accumulating evidence supports that long non-coding RNAs (lncRNAs) are implicated in the
tumorigenesis and progression of glioma. Recent studies find that lncRNA long intergenic …

Circular RNA circSCAF11 accelerates the glioma tumorigenesis through the miR-421/SP1/VEGFA axis

Q Meng, S Li, Y Liu, S Zhang, J Jin, Y Zhang… - … Therapy-Nucleic Acids, 2019 - cell.com
Circular RNAs (circRNAs) are a novel category of non-coding RNAs, and they have been
identified to participate in glioma tumorigenesis. Here we investigated the functions of …

LncRNA NEAT1 regulates the proliferation and production of the inflammatory cytokines in rheumatoid arthritis fibroblast-like synoviocytes by targeting miR-204-5p

J Xiao, R Wang, W Zhou, X Cai, Z Ye - Human cell, 2021 - Springer
Rheumatoid arthritis (RA) is a chronic inflammatory disease, featured by erosive arthritis,
which will eventually lead to deprivation normal functions of the joint and joint …

m6A reader IGF2BP2-stabilized CASC9 accelerates glioblastoma aerobic glycolysis by enhancing HK2 mRNA stability

H Liu, S Qin, C Liu, L Jiang, C Li, J Yang, S Zhang… - Cell Death …, 2021 - nature.com
Abstract N6-methyladenosine (m6A) has been identified to exert critical roles in human
cancer; however, the regulation of m6A modification on glioblastoma multiforme (GBM) and …

M2 bone marrow-derived macrophage-derived exosomes shuffle microRNA-21 to accelerate immune escape of glioma by modulating PEG3

F Yang, T Wang, P Du, H Fan, X Dong, H Guo - Cancer Cell International, 2020 - Springer
Background Growing studies have focused on the role of microRNA-21 (miR-21) in glioma,
thus our objective was to discuss the effect of M2 bone marrow-derived macrophage …

STAT3‐induced upregulation of lncRNA ABHD11‐AS1 promotes tumour progression in papillary thyroid carcinoma by regulating miR‐1301‐3p/STAT3 axis and PI3K …

J Wen, H Wang, T Dong, P Gan, H Fang, S Wu… - Cell …, 2019 - Wiley Online Library
Objectives Emerging evidences indicated the importance of long non‐coding RNAs
(lncRNAs) in the tumorigenesis and deterioration of malignant tumours. To our knowledge …