Ischemia/reperfusion (IR) injury occurs in many organs and tissues, and contributes to
morbidity and mortality worldwide. Melatonin, an endogenously produced indolamine …

Ischemic stroke occurs when the arteries supplying blood to the brain are narrowed or
blocked, inducing damage to brain tissue due to a lack of blood supply. One effective way to …

Accumulating evidence suggests that formation of peroxynitrite (ONOO–) in the cerebral
vasculature contributes to the progression of ischemic damage, while the underlying …

Septic encephalopathy (SE) is a critical factor determining sepsis mortality. Vascular
inflammation is known to be involved in SE, but the molecular events that lead to the …

Neural aging as a progressive loss of function involves central and peripheral postmitotic
neurons and neural stem cells (NSCs). It promotes neurodegeneration, impairs …

Melatonin is produced and released by the pineal gland in a circadian rhythm. This
neurohormone has proven to be an antioxidant and anti-inflammatory molecule able to …

Ischemic stroke is an acute cerebrovascular disease and the third most common cause of
death after ischemic heart disease. Increasing attention is being paid to finding effective …

Abstract Background Salvianolic acid A (SAA) is obtained from Chinese herb Salviae
Miltiorrhizae Bunge (Labiatae), has been reported to have the protective effects against …

Severe hypoglycemia has a detrimental impact on the cerebrovasculature, but the molecular
events that lead to the disruption of the integrity of the tight junctions remain unclear. Here …

Lower global cognitive function scores are a common symptom of autism spectrum disorders
(ASD s). This study investigates the effects of melatonin on hippocampal serine/threonine …