Cell–cell communication: new insights and clinical implications

J Su, Y Song, Z Zhu, X Huang, J Fan, J Qiao… - Signal Transduction and …, 2024 - nature.com
Multicellular organisms are composed of diverse cell types that must coordinate their
behaviors through communication. Cell–cell communication (CCC) is essential for growth …

Retinal ganglion cell repopulation for vision restoration in optic neuropathy: a roadmap from the RReSTORe Consortium

JR Soucy, EA Aguzzi, J Cho, MJ Gilhooley… - Molecular …, 2023 - Springer
Retinal ganglion cell (RGC) death in glaucoma and other optic neuropathies results in
irreversible vision loss due to the mammalian central nervous system's limited regenerative …

Deep Spectral Library of Mice Retina for Myopia Research: Proteomics Dataset generated by SWATH and DIA-NN

YH Sze, DYY Tse, B Zuo, KK Li, Q Zhao, X Jiang… - Scientific data, 2024 - nature.com
The retina plays a crucial role in processing and decoding visual information, both in normal
development and during myopia progression. Recent advancements have introduced a …

Deciphering brain cellular and behavioral mechanisms: Insights from single‐cell and spatial RNA sequencing

R Chen, P Nie, J Wang, GZ Wang - Wiley Interdisciplinary …, 2024 - Wiley Online Library
The brain is a complex computing system composed of a multitude of interacting neurons.
The computational outputs of this system determine the behavior and perception of every …

Emerging therapeutic strategies for optic nerve regeneration

Q Zhang, J Tang, L Liu, Z Liu, J Xue, J Ge… - Trends in …, 2024 - cell.com
The optic nerve, comprising axons from retinal ganglion cells (RGCs), is a component of the
central nervous system (CNS) that generally exhibits a limited regeneration capacity …

[HTML][HTML] Single-cell multiomics profiling reveals heterogeneity of Müller cells in the oxygen-induced retinopathy model

X Yao, Z Li, Y Lei, Q Liu, S Chen… - … & Visual Science, 2024 - tvst.arvojournals.org
Purpose: Retinal neovascularization poses heightened risks of vision loss and blindness.
Despite its clinical significance, the molecular mechanisms underlying the pathogenesis of …

Non-invasive single cell aptasensing in live cells and animals

EA Osman, TP Rynes, YL Wang, K Mruk… - Chemical …, 2024 - pubs.rsc.org
We report a genetically encoded aptamer biosensor platform for non-invasive measurement
of drug distribution in cells and animals. We combined the high specificity of aptamer …

Emergence of input selective recurrent dynamics via information transfer maximization

I Kanemura, K Kitano - Scientific Reports, 2024 - nature.com
Network structures of the brain have wiring patterns specialized for specific functions. These
patterns are partially determined genetically or evolutionarily based on the type of task or …

Recent Achievements in the Heterogeneity of Mammalian and Human Retinal Pigment Epithelium: In Search of a Stem Cell

LA Rzhanova, YV Markitantova, MA Aleksandrova - Cells, 2024 - mdpi.com
Retinal pigment epithelium (RPE) cells are important fundamentally for the development and
function of the retina. In this regard, the study of the morphological and molecular properties …

Comprehensive single-cell atlas of the mouse retina

J Li, J Choi, X Cheng, J Ma, S Pema, JR Sanes… - Iscience, 2024 - cell.com
Single-cell RNA sequencing (scRNA-seq) has advanced our understanding of cellular
heterogeneity by characterizing cell types across tissues and species. While several mouse …