[HTML][HTML] Epigenetic regulation of diverse regulated cell death modalities in cardiovascular disease: Insights into necroptosis, pyroptosis, ferroptosis, and cuproptosis

C Chen, J Wang, S Zhang, X Zhu, J Hu, C Liu, L Liu - Redox Biology, 2024 - Elsevier
Cell death constitutes a critical component of the pathophysiology of cardiovascular
diseases. A growing array of non-apoptotic forms of regulated cell death (RCD)—such as …

Lactate and Lysine Lactylation of Histone Regulate Transcription in Cancer

Y Yang, N Luo, Z Gong, W Zhou, Y Ku, Y Chen - Heliyon, 2024 - cell.com
Histone lysine modifications were well-established epigenetic markers, with many types
identified and extensively studied. The discovery of histone lysine lactylation had revealed a …

The catalytic activity of methyltransferase METTL15 is dispensable for its role in mitochondrial ribosome biogenesis

CD Mutti, L Van Haute, M Minczuk - RNA biology, 2024 - Taylor & Francis
Ribosomes are large macromolecular complexes composed of both proteins and RNA, that
require a plethora of factors and post-transcriptional modifications for their biogenesis. In …

Mitochondrial ribosome biogenesis and redox sensing

M Brischigliaro, A Sierra‐Magro, A Ahn… - FEBS Open …, 2024 - Wiley Online Library
Mitoribosome biogenesis is a complex process involving RNA elements encoded in the
mitochondrial genome and mitoribosomal proteins typically encoded in the nuclear genome …

METTL Family in Health and Disease

J He, F Hao, S Song, J Zhang, H Zhou, J Zhang… - Molecular Biomedicine, 2024 - Springer
Transcription, RNA splicing, RNA translation, and post-translational protein modification are
fundamental processes of gene expression. Epigenetic modifications, such as DNA …