[HTML][HTML] Synovitis in osteoarthritis: current understanding with therapeutic implications

A Mathiessen, PG Conaghan - Arthritis research & therapy, 2017 - Springer
Modern concepts of osteoarthritis (OA) have been forever changed by modern imaging
phenotypes demonstrating complex and multi-tissue pathologies involving cartilage …

[HTML][HTML] Measurement and clinical significance of lipid peroxidation as a biomarker of oxidative stress: oxidative stress in diabetes, atherosclerosis, and chronic …

F Ito, Y Sono, T Ito - Antioxidants, 2019 - mdpi.com
Endothelial dysfunction is one of the initial steps in the pathogenesis of atherosclerosis and
development of cardiovascular disease in patients with diabetes mellitus. Several risk …

The role of inflammatory and anti‐inflammatory cytokines in the pathogenesis of osteoarthritis

P Wojdasiewicz, ŁA Poniatowski… - Mediators of …, 2014 - Wiley Online Library
Osteoarthritis (OA) is the most common chronic disease of human joints. The basis of
pathologic changes involves all the tissues forming the joint; already, at an early stage, it has …

[HTML][HTML] Osteoarthritis as an inflammatory disease (osteoarthritis is not osteoarthrosis!)

F Berenbaum - Osteoarthritis and cartilage, 2013 - Elsevier
Osteoarthritis (OA) has long been considered a “wear and tear” disease leading to loss of
cartilage. OA used to be considered the sole consequence of any process leading to …

[HTML][HTML] Osteoarthritis: a disease of the joint as an organ

RF Loeser, SR Goldring, CR Scanzello… - Arthritis and …, 2012 - ncbi.nlm.nih.gov
Osteoarthritis (OA) is the most common form of arthritis and a major cause of pain and
disability in older adults (1). Often OA is referred to as degenerative joint disease “(DJD)” …

Role of proinflammatory cytokines in the pathophysiology of osteoarthritis

M Kapoor, J Martel-Pelletier, D Lajeunesse… - Nature Reviews …, 2011 - nature.com
Osteoarthritis (OA) is associated with cartilage destruction, subchondral bone remodeling
and inflammation of the synovial membrane, although the etiology and pathogenesis …

Inflammatory mediators in osteoarthritis: A critical review of the state-of-the-art, current prospects, and future challenges

M Rahmati, A Mobasheri, M Mozafari - Bone, 2016 - Elsevier
Osteoarthritis (OA) has traditionally been defined as a prototypical non-inflammatory
arthropathy, but today there is compelling evidence to suggest that it has an inflammatory …

[HTML][HTML] Intraarticular injections (corticosteroid, hyaluronic acid, platelet rich plasma) for the knee osteoarthritis

E Ayhan, H Kesmezacar, I Akgun - World journal of orthopedics, 2014 - ncbi.nlm.nih.gov
Osteoarthritis (OA) is a complex “whole joint” disease pursued by inflammatory mediators,
rather than purely a process of “wear and tear”. Besides cartilage degradation, synovitis …

Role of inflammation in the pathogenesis of osteoarthritis: latest findings and interpretations

J Sokolove, CM Lepus - Therapeutic advances in …, 2013 - journals.sagepub.com
Osteoarthritis (OA) has traditionally been classified as a noninflammatory arthritis; however,
the dichotomy between inflammatory and degenerative arthritis is becoming less clear with …

[HTML][HTML] Nothing boring about boron

L Pizzorno - Integrative Medicine: A Clinician's Journal, 2015 - ncbi.nlm.nih.gov
The trace mineral boron is a micronutrient with diverse and vitally important roles in
metabolism that render it necessary for plant, animal, and human health, and as recent …