The devil is in the details: Whole slide image acquisition and processing for artifacts detection, color variation, and data augmentation: A review

N Kanwal, F Pérez-Bueno, A Schmidt, K Engan… - Ieee …, 2022 - ieeexplore.ieee.org
Whole Slide Images (WSI) are widely used in histopathology for research and the diagnosis
of different types of cancer. The preparation and digitization of histological tissues leads to …

[HTML][HTML] Stain normalization methods for histopathology image analysis: A comprehensive review and experimental comparison

MZ Hoque, A Keskinarkaus, P Nyberg, T Seppänen - Information Fusion, 2024 - Elsevier
The advent of whole slide imaging has brought advanced computer-aided diagnosis via
medical imaging and artificial intelligence technologies in digital pathology. The …

Structure-preserving color normalization and sparse stain separation for histological images

A Vahadane, T Peng, A Sethi… - IEEE transactions on …, 2016 - ieeexplore.ieee.org
Staining and scanning of tissue samples for microscopic examination is fraught with
undesirable color variations arising from differences in raw materials and manufacturing …

A deep convolutional neural network for segmenting and classifying epithelial and stromal regions in histopathological images

J Xu, X Luo, G Wang, H Gilmore, A Madabhushi - Neurocomputing, 2016 - Elsevier
Epithelial (EP) and stromal (ST) are two types of tissues in histological images. Automated
segmentation or classification of EP and ST tissues is important when developing …

Artificial intelligence predicts immune and inflammatory gene signatures directly from hepatocellular carcinoma histology

Q Zeng, C Klein, S Caruso, P Maille, NG Laleh… - Journal of …, 2022 - Elsevier
Background & Aims Patients with hepatocellular carcinoma (HCC) displaying
overexpression of immune gene signatures are likely to be more sensitive to …

Adaptive color deconvolution for histological WSI normalization

Y Zheng, Z Jiang, H Zhang, F Xie, J Shi… - Computer methods and …, 2019 - Elsevier
Abstract Background and Objective Color consistency of histological images is significant for
developing reliable computer-aided diagnosis (CAD) systems. However, the color …

Deep learning in digital pathology for personalized treatment plans of cancer patients

Z Wen, S Wang, DM Yang, Y Xie, M Chen… - Seminars in diagnostic …, 2023 - Elsevier
Over the past decade, many new cancer treatments have been developed and made
available to patients. However, in most cases, these treatments only benefit a specific …

Application of non-negative matrix factorization in oncology: one approach for establishing precision medicine

R Hamamoto, K Takasawa, H Machino… - Briefings in …, 2022 - academic.oup.com
The increase in the expectations of artificial intelligence (AI) technology has led to machine
learning technology being actively used in the medical field. Non-negative matrix …

SD-layer: stain deconvolutional layer for CNNs in medical microscopic imaging

R Duggal, A Gupta, R Gupta, P Mallick - … 11-13, 2017, Proceedings, Part III …, 2017 - Springer
Abstract Convolutional Neural Networks (CNNs) are typically trained in the RGB color
space. However, in medical imaging, we believe that pixel stain quantities offer a …

[HTML][HTML] Blind color deconvolution, normalization, and classification of histological images using general super Gaussian priors and Bayesian inference

F Pérez-Bueno, M Vega, MA Sales… - Computer Methods and …, 2021 - Elsevier
Abstract Background and Objective: Color variations in digital histopathology severely
impact the performance of computer-aided diagnosis systems. They are due to differences in …