[HTML][HTML] Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases

AL Cardoso, A Fernandes, JA Aguilar-Pimentel… - Ageing research …, 2018 - Elsevier
Objective Use of the frailty index to measure an accumulation of deficits has been proven a
valuable method for identifying elderly people at risk for increased vulnerability, disease …

Relationship between depression and frailty in older adults: a systematic review and meta-analysis

P Soysal, N Veronese, T Thompson, KG Kahl… - Ageing research …, 2017 - Elsevier
Aim Depression and frailty are prevalent and burdensome in older age. However, the
relationships between these entities are unclear and no quantitative meta-analysis exists …

Different cognitive frailty models and health-and cognitive-related outcomes in older age: from epidemiology to prevention

F Panza, M Lozupone, V Solfrizzi… - Journal of …, 2018 - content.iospress.com
Frailty, a critical intermediate status of the aging process that is at increased risk for negative
health-related events, includes physical, cognitive, and psychosocial domains or …

Depression and frailty in later life: a systematic review

L Vaughan, AL Corbin, JS Goveas - Clinical interventions in aging, 2015 - Taylor & Francis
Frailty and depression are important issues affecting older adults. Depressive syndrome
may be difficult to clinically disambiguate from frailty in advanced old age. Current reviews …

[HTML][HTML] Cognitive frailty: rational and definition from an (IANA/IAGG) international consensus group

E Kelaiditi, M Cesari, M Canevelli, GA Van Kan… - The Journal of nutrition …, 2013 - Elsevier
The frailty syndrome has recently attracted attention of the scientific community and public
health organizations as precursor and contributor of age-related conditions (particularly …

Frailty and cognitive impairment—a review of the evidence and causal mechanisms

DA Robertson, GM Savva, RA Kenny - Ageing research reviews, 2013 - Elsevier
Incidence rates of cognitive impairment and dementia are rising with the ageing population.
Meanwhile, the limited success of current treatments has led to a search for early markers of …

Successful aging: Advancing the science of physical independence in older adults

SD Anton, AJ Woods, T Ashizawa, D Barb… - Ageing research …, 2015 - Elsevier
The concept of 'successful aging'has long intrigued the scientific community. Despite this
long-standing interest, a consensus definition has proven to be a difficult task, due to the …

[HTML][HTML] Effects of social isolation, loneliness and frailty on health outcomes and their possible mediators and moderators in community-dwelling older adults: A …

F Mehrabi, F Béland - Archives of gerontology and geriatrics, 2020 - Elsevier
Abstract Background/Objectives Over the past decade, the quantity and quality of social
relationships in later life have become one of the main challenges facing an aging society …

The essence of frailty: a systematic review and qualitative synthesis on frailty concepts and definitions

U Junius-Walker, G Onder, D Soleymani… - European journal of …, 2018 - Elsevier
Background One of the major threats looming over the growing older population is frailty. It is
a distinctive health state characterised by increased vulnerability to internal and external …

Impact of aging on the auditory system and related cognitive functions: a narrative review

DMP Jayakody, PL Friedland, RN Martins… - Frontiers in …, 2018 - frontiersin.org
Age-related hearing loss (ARHL), presbycusis, is a chronic health condition that affects
approximately one-third of the world's population. The peripheral and central hearing …