A number of reports have recently been published describing the discovery and optimization
of bromo and extraterminal inhibitors which are selective for the second bromodomain …

An intermediate in the synthesis of numerous antiviral protease inhibitors is the glutamine
analogue,(3 S)-pyrrolid-2-one-3-yl-l-alanine. Preparations of compounds based on this …

naphthyridinone compounds as modulators of an adenosine receptor are provided. The
compounds may find use as therapeutic agents for the treatment of diseases mediated …

Aminopyrazine compounds as modulators of an adenosine receptor are provided. The
compounds may find use as therapeutic agents for the treatment of diseases mediated …

Spin labels are a useful tool towards the study of protein conformation and enable the
mapping of interactions between specific positions within these systems. Synthetic routes …

US11192900B2 - Substituted 1,6-dihydropyridinones and 1,2-dihydroisoquinolinones as
bet inhibitors - Google Patents US11192900B2 - Substituted 1,6-dihydropyridinones and 1,2-dihydroisoquinolinones …

2022-05-03 Assigned to SPARCBIO LLC reassignment SPARCBIO LLC ASSIGNMENT OF
ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: CHAKRAVARTY …

The genomes of eukaryotic organisms are highly organ-20 ised within the nucleus of the
cell. The long strands of The invention is directed to compounds of formula (I) duplex DNA …

US11273146B2 - Benzofuran derivatives and their use as bromodomain inhibitors - Google
Patents US11273146B2 - Benzofuran derivatives and their use as bromodomain inhibitors …

2019205984 A1 8/2019 104341386 A 2/2015 107221611 A 9/2017 112055709 A 12/2020
3230277 B1 9/2019 WO2003030909 A1 4/2003 2005047285 Al 5/2005 WO2005040151 A1 …