Aims Compulsive ethanol intake, characterized by persistent consumption despite negative
consequences, is an addictive behavior identified by the DSM-5 as a central criterion in …

The transition from hedonic alcohol drinking to problematic drinking is a hallmark of alcohol
use disorder that occurs only in a subset of drinkers. This transition requires long-lasting …

Alterations to the LRRK2 gene have been associated with Parkinson's disease and alcohol
consumption in animals and humans. Furthermore, these disorders are strongly related to …

Alcohol consumption is associated with alterations in memory and learning processes in
humans and animals. In this context, research models such as the zebrafish (Danio rerio) …

Abstract Binge Eating Disorder (BED) is among the most prevalent eating disorders
worldwide. It is characterized by recurrent episodes of excessive consumption of palatable …

Gene prioritization approaches are useful tools to explore and select candidate genes in
transcriptome studies. Knowing the importance of processes such as neuronal activity …

Due to its multifactorial and yet to be fully understood origin, ethanol addiction is a field that
still requires studies for the elucidation of novel genes and pathways that potentially …

Thiamine deficiency (TD) has been used as an experimental model in rodents to study the
molecular mechanisms of neurodegeneration and its association with behavioral changes …

Alcohol use disorder (AUD) is a primary, chronic and relapsing disease of brain reward,
motivation and memory, which is associated with several comorbidities, including major …

Background: Genetics influence the vulnerability to alcohol use disorders, and among the
implicated genes, three previous studies have provided evidences for the involvement of …