Diosmin alleviates doxorubicin-induced liver injury via modulation of oxidative stress-mediated hepatic inflammation and apoptosis via NfkB and MAPK pathway: A …
AF AlAsmari, M Alharbi, F Alqahtani, F Alasmari… - Antioxidants, 2021 - mdpi.com
Hepatotoxicity caused by chemotherapeutic drugs (eg, doxorubicin) is of critical concern in
cancer therapy. This study focused on investigating the modulatory effects of diosmin …
cancer therapy. This study focused on investigating the modulatory effects of diosmin …
[HTML][HTML] N-Acetylcysteine may exert hepatoprotective effect by regulating Meteorin-Like levels in Adriamycin-induced liver injury
Adriamycin (ADR) is an important chemotherapeutic drug, but it has serious side effects
such as hepatotoxicity. This study aimed to evaluate whether N-acetylcysteine (NAC) has …
such as hepatotoxicity. This study aimed to evaluate whether N-acetylcysteine (NAC) has …
Therapeutic effects of thymoquinone in doxorubicin‐induced hepatotoxicity via oxidative stress, inflammation and apoptosis
Cancer is a lethal disease that is characterized by uncontrolled cell division and
proliferation, and it results in death in many organisms. Doxorubicin (DOX) is a therapeutic …
proliferation, and it results in death in many organisms. Doxorubicin (DOX) is a therapeutic …
Misoprostol alleviates paclitaxel-induced liver damage through its antioxidant and anti-apoptotic effects
Backgrounds Anticancer drugs may damage non-target cells and tissues. One of the biggest
reasons for changing or stopping chemotherapy regimens is these adverse effects …
reasons for changing or stopping chemotherapy regimens is these adverse effects …
Protective potential of misoprostol against kidney alteration via alleviating oxidative stress in rat following exposure to paclitaxel
İ Aktaş, A Yahyazadeh - Tissue and Cell, 2022 - Elsevier
The present study investigated the protective effect of misoprostol (MSP)(0.2 mg/kg, oral)
against kidney injury caused by paclitaxel (PLX)(2 mg/kg, intraperitoneal) in female Sprague …
against kidney injury caused by paclitaxel (PLX)(2 mg/kg, intraperitoneal) in female Sprague …
[PDF][PDF] Propolis protective effects against doxorubicin-induced multi-organ toxicity via suppression of oxidative stress, inflammation, apoptosis, and histopathological …
EK Mohamed, AA Osman, AM Moghazy… - … Res. Appl. Chem, 2021 - researchgate.net
Doxorubicin (DOX) is effective chemotherapy in several malignancies, but large-scale
toxicities limit its clinical usefulness. Propolis has been reported to exhibit a broad spectrum …
toxicities limit its clinical usefulness. Propolis has been reported to exhibit a broad spectrum …
Effect of curcumin on lipid profile, fibrosis, and apoptosis in liver tissue in abemaciclib-administered rats
Abemaciclib (ABEM) is an important antitumor agent for breast cancer treatment. However,
the side-effects of ABEM are unclear in the liver. This study investigated the protective effect …
the side-effects of ABEM are unclear in the liver. This study investigated the protective effect …
[PDF][PDF] Silymarin protects kidneys from paclitaxel-induced nephrotoxicity.
The effects of drugs used in cancer treatment are not only specific to cancer cells but also
negatively affect healthy cells. This study, it was aimed to investigate the protective effects of …
negatively affect healthy cells. This study, it was aimed to investigate the protective effects of …
A synthetic prostaglandin E1 analogue, misoprostol, ameliorates paclitaxel-induced oxidative damage in rat brain
The main objective of our study was to examine the protection of misoprostol (MP) on
paclitaxel (PAX) side effects in rat brains. Twenty-eight female Sprague-Dawley rats were …
paclitaxel (PAX) side effects in rat brains. Twenty-eight female Sprague-Dawley rats were …
Biochemical and Histopathological Investigation of the Protective Effect of Lutein in Rat Kidney Exposed to Cisplatin
Aim: The aim of this study was to determine the protection of lutein (L)(100 mg/kg, orally)
against kidney damage caused by cisplatin (Cis)(10mg/kg, intraperitoneal). Materials and …
against kidney damage caused by cisplatin (Cis)(10mg/kg, intraperitoneal). Materials and …