Neovascular age-related macular degeneration (NVAMD) is the most prevalent choroidal
vascular disease, and diabetic retinopathy (DR) and retinal vein occlusion (RVO) are the …

Diabetic macular edema (DME) is a critical complication of diabetic retinopathy, a condition
that arises from the breakdown of the blood–retinal barrier and the consequent increase in …

Purpose To assess and compare early changes in neuroinflammatory and vascular
parameters in diabetic macular edema (DME) with subfoveal neuroretinal detachment …

Purpose: Corticosteroids remain the mainstay of treatment for inflammatory diseases almost
80 years after their first clinical use. Topical ophthalmic formulations of corticosteroids have …

Background Diabetic retinopathy is a diabetic microvascular complication. Pyroptosis, as a
way of inflammatory death, plays an important role in the occurrence and development of …

The mammalian prokineticins family comprises two conserved proteins, EG-VEGF/PROK1
and Bv8/PROK2, and their two highly related G protein-coupled receptors, PKR1 and PKR2 …

Tie2 is a tyrosine kinase receptor located predominantly on vascular endothelial cells that
plays a central role in vascular stability. Angiopoietin-1 (Angpt1), produced by perivascular …

Purpose This study evaluated the potential safety, efficacy, and durability advantages of
investigational triamcinolone acetonide suspension (CLS-TA; Clearside Biomedical …

Over the past decade, great strides have been made in the management of diabetic macular
edema (DME). Therapeutic alternatives now include focal/grid laser photocoagulation, vitreo …

Purpose To identify biomarkers for predicting response to anti− vascular endothelial growth
factor (VEGF) therapy in diabetic macular edema (DME) and evaluate any links between …