Mitogen‐activated protein kinase (MAPK) signaling pathways organize a great constitution
network that regulates several physiological processes, like cell growth, differentiation, and …

Cannabidiol (CBD), the major non-psychoactive phytocannabinoid of Cannabis sativa L., is
one of the most studied compounds in pharmacotherapeutic approaches to treat oxidative …

Background Doxorubicin is currently the most effective chemotherapeutic drug used to treat
breast cancer. It has, however, been shown that doxorubicin can induce drug resistance …

The Ras/Raf/extracellular signal‐regulated kinase (ERK) signaling pathway plays a crucial
role in almost all cell functions and therefore requires exquisite control of its spatiotemporal …

Cancer can be perceived as a disease of communication between and within cells. The
aberrations are pleiotropic, but mitogen-activated protein kinase (MAPK) pathways feature …

Oxidative stress and AKT serine-threonine kinase (AKT) are responsible for regulating
several cell functions of cancer cells. Several natural products modulate both oxidative …

Sirtuins are a family of NAD+-dependent deacylases with numerous physiological and
pathological implications, which lately became an attractive therapeutic target. Sirtuin …

Melanoma is the most aggressive skin cancer in humans that often expresses MHC class II
(MHC II) molecules, which could make these tumors eliminable by the immune system …

The sigma-1 receptor, an endoplasmic reticulum-associated molecular chaperone, is
attracting great interest as a potential target for neuroprotective treatments. We provide the …

Simple Summary Deregulation of the FGF/FGFR axis is associated with many types of
cancer and contributes to the development of chemoresistance, limiting the effectiveness of …