Cytokine stimulation of epithelial cancer cells: the similar and divergent functions of IL-4 and IL-13
MA Hallett, KT Venmar, B Fingleton - Cancer research, 2012 - AACR
The Th2 cytokines interleukin (IL)-4 and-13 are acknowledged regulators of lymphocyte
proliferation and activation. They have also been well studied in the regulation of various …
proliferation and activation. They have also been well studied in the regulation of various …
Possible roles of interleukin-4 and-13 and their receptors in gastric and colon cancer
X Song, B Traub, J Shi, M Kornmann - International Journal of Molecular …, 2021 - mdpi.com
Interleukin (IL)-4 and-13 are structurally and functionally related cytokines sharing common
receptor subunits. They regulate immune responses and, moreover, are involved in the …
receptor subunits. They regulate immune responses and, moreover, are involved in the …
Association of inflammation-related and microRNA gene expression with cancer-specific mortality of colon adenocarcinoma
Purpose: Inflammatory genes and microRNAs have roles in colon carcinogenesis; therefore,
they may provide useful biomarkers for colon cancer. This study examines the potential …
they may provide useful biomarkers for colon cancer. This study examines the potential …
[HTML][HTML] Genetic polymorphisms of IL-6 promoter in cancer susceptibility and prognosis: a meta-analysis
X Peng, J Shi, W Sun, X Ruan, Y Guo, L Zhao, J Wang… - Oncotarget, 2018 - ncbi.nlm.nih.gov
IL-6 is critical for tumorigenesis. However, previous studies on the association of IL-6
promoter polymorphisms with predisposition to different cancer types are somewhat …
promoter polymorphisms with predisposition to different cancer types are somewhat …
Statistical meta-analysis to investigate the association between the Interleukin-6 (IL-6) gene polymorphisms and cancer risk
A good number of genome-wide association studies (GWAS), including meta-analyses,
reported that single nucleotide polymorphisms (SNPs) of the IL-6 gene are significantly …
reported that single nucleotide polymorphisms (SNPs) of the IL-6 gene are significantly …
TLR-3 polymorphism is an independent prognostic marker for stage II colorectal cancer
FA Castro, A Försti, S Buch, H Kalthoff, C Krauss… - European Journal of …, 2011 - Elsevier
BACKGROUND: Clinicopathologic stage is still the main parameter to evaluate the
prognosis of newly diagnosed colorectal cancer (CRC) patients. Although molecular …
prognosis of newly diagnosed colorectal cancer (CRC) patients. Although molecular …
Genetic variants in interleukin genes are associated with breast cancer risk and survival in a genetically admixed population: the Breast Cancer Health Disparities …
ML Slattery, JS Herrick, G Torres-Mejia… - …, 2014 - academic.oup.com
Interleukins (ILs) are key regulators of immune response. Genetic variation in IL genes may
influence breast cancer risk and mortality given their role in cell growth, angiogenesis and …
influence breast cancer risk and mortality given their role in cell growth, angiogenesis and …
Associations of common IL-4 gene polymorphisms with cancer risk: A meta-analysis
Y Jia, X Xie, X Shi, S Li - Molecular medicine reports, 2017 - spandidos-publications.com
Cancer incidence is dramatically increasing worldwide, therefore improved prediction and
therapeutic methods are needed. Single nucleotide polymorphisms in cytokine genes may …
therapeutic methods are needed. Single nucleotide polymorphisms in cytokine genes may …
− 251 T/A polymorphism of the interleukin-8 gene and cancer risk: a HuGE review and meta-analysis based on 42 case–control studies
N Wang, R Zhou, C Wang, X Guo, Z Chen… - Molecular biology …, 2012 - Springer
Abstract The− 251T/A (rs4073), a single nucleotide polymorphism, has been identified in the
promoter region of the interleukin-8 (IL-8) gene. It's presence could influence the production …
promoter region of the interleukin-8 (IL-8) gene. It's presence could influence the production …
Significance of −1082A/G polymorphism of IL10 gene for progression of colorectal cancer and IL-10 expression
The role of functional polymorphism within IL10 (rs1800896) in colorectal cancer (CRC) still
remains elusive. The aim of present study was to investigate the significance of− 1082A/G …
remains elusive. The aim of present study was to investigate the significance of− 1082A/G …