The importance of nicotinamide adenine dinucleotide (NAD+) in human physiology is well
recognized. As the NAD+ concentration in human skin, blood, liver, muscle and brain are …

Mitochondria and mitochondria‐mediated signalling pathways are known to control synaptic
signalling, as well as long‐lasting changes in neuronal structure and function. Mitochondrial …

Biosynthesis and regulation of nicotinamide adenine dinucleotide (NAD+) has recently
gained a lot of attention. A systemic decline in NAD+ across many tissues is associated with …

Nicotinamide mononucleotide (NMN), a crucial intermediate in NAD+ synthesis, can rapidly
transform into NAD+ within the body after ingestion. NMN plays a pivotal role in several …

Nicotinamide mononucleotide (NMN), the direct precursor of nicotinamide adenine
dinucleotide (NAD+), is involved in the regulation of many physiological and metabolic …

Pathological deterioration of mitochondrial function is increasingly linked with multiple
degenerative illnesses as a mediator of a wide range of neurologic and age-related chronic …

There have been many discussions on longevity from ancient times to the present day. In the
Laozi, it is said,“Heaven and earth are long and enduring because they do not arise from …

The fluorescent probe pair, NBD-B2 and Styryl-51F, selectively detects NMN over citric acid.
NBD-B2 exhibits increased fluorescence, while Styryl-51F shows decreased fluorescence …

Nicotinamide mononucleotide (NMN), a naturally occurring biologically active nucleotide,
mainly functions via mediating the biosynthesis of NAD+. In recent years, its excellent …

Retinal ischemia/reperfusion (I/R) injury can cause severe vision impairment. Retinal I/R
injury is associated with pathological increases in reactive oxygen species and …