Advances in detection of antipsychotics in biological matrices

L Patteet, D Cappelle, KE Maudens, CL Crunelle… - Clinica chimica acta, 2015 - Elsevier
Measuring antipsychotic concentrations in human matrices is important for both therapeutic
drug monitoring and forensic toxicology. This review provides a critical overview of the …

An electrochemical sensor for clozapine at ruthenium doped TiO2 nanoparticles modified electrode

NP Shetti, DS Nayak, SJ Malode… - Sensors and Actuators B …, 2017 - Elsevier
A new modified sensor based on carbon paste electrode (CPE) was developed using
ruthenium doped titanium dioxide nanoparticles (Ru-TiO 2). In this work, we demonstrated …

Construction of Pd-Ag/g-C3N4/CPE electrochemical nanosensor for simultaneous determination of clozapine and quetiapine antipsychotic drugs

Z Alipour, SK Hassaninejad-Darzi… - Journal of Alloys and …, 2023 - Elsevier
A sensitive electrochemical procedure assisted by multivariate optimization approaches is
applied for the simultaneous determination of antipsychotic drugs including clozapine (CLZ) …

Determination of seven selected antipsychotic drugs in human plasma using microextraction in packed sorbent and gas chromatography–tandem mass spectrometry

BM Da Fonseca, IED Moreno, M Barroso… - Analytical and …, 2013 - Springer
A method using microextraction by packed sorbent (MEPS) and gas chromatography–
tandem mass spectrometry (GC-MS/MS) is described for the determination of seven …

Highly sensitive MXene-based voltammetric sensor for nanomolar clozapine detection

C Zhou, Y Sima, Y Wu, Y Wei, D Tuo, S Shi… - Diamond and Related …, 2024 - Elsevier
Clozapine is vital for managing schizophrenia and other psychiatric disorders. As a potent
medication with risks of severe side effects, accurate detection ensures effective treatment …

Fabrication of MWCNTs and Ru doped TiO2 nanoparticles composite carbon sensor for biomedical application

NP Shetti, DS Nayak, SJ Malode… - ECS Journal of Solid …, 2018 - iopscience.iop.org
Carbon-based resources introduced as sensing tools enormously in recent years for
biomedical and biological applications. In the current research, a novel carbon-based …

Fabrication of a molecularly imprinted polymer-based electrochemical sensor for the selective assay of antipsychotic drug clozapine and performance comparison with …

A Kul, F Budak, A Cetinkaya, SI Kaya, S Al, O Sagirli… - Talanta, 2025 - Elsevier
Clozapine (CLO) is an atypical antipsychotic drug indicated for the treatment of
schizophrenia. The treatment effectiveness of CLO is better than that of other atypical …

Chromatographic Methods for the Analysis of the Antipsychotic Drug Clozapine and Its Major Metabolites: A Review

H Hrichi, N Kouki, NAA Elkanzi - Journal of Chromatographic …, 2024 - academic.oup.com
Abstract Clozapine (CLZ), a second-generation antipsychotic, can effectively reduce
schizophrenia, bipolar disorder and major depression symptoms. This review provides an …

Rapid determination of some psychotropic drugs in complex matrices by tandem dispersive liquid–liquid microextraction followed by high performance liquid …

A Asghari, E Fahimi, M Bazregar, M Rajabi… - … of chromatography B, 2017 - Elsevier
Simple and rapid determinations of some psychotropic drugs in some pharmaceutical
wastewater and human plasma samples were successfully accomplished via the tandem …

Preparation of magnetic ODS-PAN thin-films for microextraction of quetiapine and clozapine in plasma and urine samples followed by HPLC-UV detection

D Li, J Zou, PS Cai, CM Xiong, JL Ruan - Journal of pharmaceutical and …, 2016 - Elsevier
In this study, conventional thin-film microextraction (TFME) was endowed with magnetic by
introducing superparamagnetic SiO 2@ Fe 3 O 4 nanoparticles in thin-films. Novel magnetic …