Current progress in tendon and ligament tissue engineering

WL Lim, LL Liau, MH Ng, SR Chowdhury… - Tissue engineering and …, 2019 - Springer
Background: Tendon and ligament injuries accounted for 30% of all musculoskeletal
consultations with 4 million new incidences worldwide each year and thus imposed a …

[HTML][HTML] Biomimetic strategies for tendon/ligament-to-bone interface regeneration

T Lei, T Zhang, W Ju, X Chen, BC Heng, W Shen… - Bioactive Materials, 2021 - Elsevier
Tendon/ligament-to-bone healing poses a formidable clinical challenge due to the complex
structure, composition, cell population and mechanics of the interface. With rapid advances …

Platelet-rich plasma for arthroscopic repair of medium to large rotator cuff tears: a randomized controlled trial

CH Jo, JS Shin, WH Shin, SY Lee… - … American journal of …, 2015 - journals.sagepub.com
Background: Two main questions about the use of platelet-rich plasma (PRP) for
regeneration purposes are its effect on the speed of healing and the quality of healing …

Does application of moderately concentrated platelet-rich plasma improve clinical and structural outcome after arthroscopic repair of medium-sized to large rotator cuff …

V Pandey, A Bandi, S Madi, L Agarwal… - Journal of shoulder and …, 2016 - Elsevier
Background Platelet-rich plasma (PRP) has the potential to improve tendon-bone healing.
The evidence is still controversial as to whether PRP application after repair of medium …

[HTML][HTML] An evidence-based evaluation on the use of platelet rich plasma in orthopedics–a review of the literature

N Hussain, H Johal, M Bhandari - Sicot-j, 2017 - ncbi.nlm.nih.gov
Within orthopedics, the use of platelet-rich plasma (PRP) has been rapidly increasing in
popularity, however, its true effectiveness has yet to be fully established. Several studies find …

Platelet-rich plasma in orthopedic therapy: a comparative systematic review of clinical and experimental data in equine and human musculoskeletal lesions

PM Brossi, JJ Moreira, TSL Machado… - BMC veterinary …, 2015 - Springer
Background This systematic review aimed to present and critically appraise the available
information on the efficacy of platelet rich plasma (PRP) in equine and human orthopedic …

The role of animal models in tendon research

MW Hast, A Zuskov, LJ Soslowsky - Bone & joint research, 2014 - boneandjoint.org.uk
Tendinopathy is a debilitating musculoskeletal condition which can cause significant pain
and lead to complete rupture of the tendon, which often requires surgical repair. Due in part …

Efficacy of platelet-rich plasma in arthroscopic repair of full-thickness rotator cuff tears: a meta-analysis

Y Cai, C Zhang, X Lin - Journal of Shoulder and Elbow Surgery, 2015 - Elsevier
Background The use of platelet-rich plasma (PRP) is an innovative clinical therapy,
especially in arthroscopic rotator cuff repair. The purpose of this study was to compare the …

Platelet-rich plasma in the pathologic processes of tendinopathy: a review of basic science studies

J Lu, H Li, Z Zhang, R Xu, J Wang, H Jin - Frontiers in Bioengineering …, 2023 - frontiersin.org
Tendinopathy is a medical condition that includes a spectrum of inflammatory and
degenerative tendon changes caused by traumatic or overuse injuries. The pathological …

New and emerging strategies in platelet‐rich plasma application in musculoskeletal regenerative procedures: General overview on still open questions and outlook

F Salamanna, F Veronesi, M Maglio… - BioMed Research …, 2015 - Wiley Online Library
Despite its pervasive use, the clinical efficacy of platelet‐rich plasma (PRP) therapy and the
different mechanisms of action have yet to be established. This overview of the literature is …