A20/tumor necrosis factor α-induced protein 3 in immune cells controls development of autoinflammation and autoimmunity: lessons from mouse models

T Das, Z Chen, RW Hendriks, M Kool - Frontiers in immunology, 2018 - frontiersin.org
Immune cell activation is a stringently regulated process, as exaggerated innate and
adaptive immune responses can lead to autoinflammatory and autoimmune diseases …

Updates in lupus genetics

Y Deng, BP Tsao - Current rheumatology reports, 2017 - Springer
Abstract Purpose of Review Our understanding on genetic basis of SLE has been advanced
through genome-wide association studies. We review recent progress in lupus genetics with …

Molecular biology of autoinflammatory diseases

J Masumoto, W Zhou, S Morikawa, S Hosokawa… - Inflammation and …, 2021 - Springer
The long battle between humans and various physical, chemical, and biological insults that
cause cell injury (eg, products of tissue damage, metabolites, and/or infections) have led to …

[HTML][HTML] Mir-483 inhibits colon cancer cell proliferation and migration by targeting TRAF1

ZY Niu, WL Li, DL Jiang, YS Li, XJ Xie - The Kaohsiung Journal of Medical …, 2018 - Elsevier
MicroRNAs are important regulators during human growth and development. Emerging
evidence indicates that microRNAs play important roles in colorectal cancer. The aim of this …

Association of TNFAIP3 and TNIP1 polymorphisms with systemic lupus erythematosus risk: a meta-analysis

X Liu, H Qin, J Wu, J Xu - Gene, 2018 - Elsevier
Object With the development of GWAS, both TNFAIP3 and TNIP1 were revealed to be
susceptibility genes of SLE. However, some other studies revealed no association between …

A De Novo Frameshift Mutation in TNFAIP3 Impairs A20 Deubiquitination Function to Cause Neuropsychiatric Systemic Lupus Erythematosus

R Duan, Q Liu, J Li, X Bian, Q Yuan, Y Li… - Journal of clinical …, 2019 - Springer
Purpose Genome-wide association study of systemic lupus erythematosus (SLE) revealed
tumor necrosis factor alpha-induced protein 3 (TNFAIP3, A20) as a susceptibility gene. Here …

Genetics of human SLE

Y Deng, BP Tsao - Dubois' Lupus Erythematosus and Related Syndromes, 2019 - Elsevier
The interplay of genetic predispositions, epigenetic changes, and environmental exposures
contributes to the complex etiology of systemic lupus erythematosus (SLE). During the last …

TNFSF13B rs9514828 C>T Polymorphism is Associated with Incidence of Atherosclerosis and Therapeutic Outcomes in Patients with Systemic Lupus Erythematosus

DR Fajar, T Rostinawati, L Hamijoyo… - … : Targets and Therapy, 2024 - Taylor & Francis
Background Systemic lupus erythematosus (SLE) is a complex autoimmune disease with
numerous clinical manifestations. Organ involvement can aggravate patients with SLE and …

Polymorphisms in TNFAIP3, but not in STAT4, BANK1, BLK, and TNFSF4, are associated with susceptibility to Takayasu arteritis

I Montúfar‑Robles, ME Soto, S Jiménez‑Morales… - Cellular …, 2021 - Elsevier
Background Takayasu arteritis (TAK) is considered a rare disease characterized by
nonspecific inflammation of the large arteries, especially the aorta and its major branches …

Associations between TNFAIP3 Polymorphisms and Rheumatoid Arthritis: A Systematic Review and Meta-Analysis Update with Trial Sequential Analysis

YH Lee, GG Song - Public Health Genomics, 2022 - karger.com
Introduction: The tumor necrosis factor alpha inducible protein 3 (TNFAIP3) gene produces
ubiquitin-editing protein A20, which inhibits nuclear factor-κB (NF-κB) activation in a variety …