Recent progress in atomistic simulation of electrical current DNA sequencing
We review recent advances in the DNA sequencing method based on measurements of
transverse electrical currents. Device configurations proposed in the literature are classified …
transverse electrical currents. Device configurations proposed in the literature are classified …
Electronic signatures of all four DNA nucleosides in a tunneling gap
Nucleosides diffusing through a 2 nm electron-tunneling junction generate current spikes of
sub-millisecond duration with a broad distribution of peak currents. This distribution narrows …
sub-millisecond duration with a broad distribution of peak currents. This distribution narrows …
Ultra-rapid DNA sequencing method with nano-transistors array based devices
JT Huang, CH Tsai - US Patent App. 11/409,793, 2006 - Google Patents
The invention disclosed a method based on nano-transistors for ultra-rapid DNA
sequencing. The method provides micro-fabricated electrodes, which are applied for …
sequencing. The method provides micro-fabricated electrodes, which are applied for …
Systems and methods for controlling position of charged polymer inside nanopore
Techniques for controlling the position of a charged polymer inside a nanopore are
provided. For example, one technique includes using electrostatic control to position a linear …
provided. For example, one technique includes using electrostatic control to position a linear …
Method and apparatus for sequencing polymers through tunneling conductance variation detection
M Zhu - US Patent 7,279,337, 2007 - Google Patents
Systems and methods of identifying molecules of polymers such as, for example, a nucleic
acid, are described. The method involves centering a bias voltage across a pair of …
acid, are described. The method involves centering a bias voltage across a pair of …
Hybridization assisted nanopore sequencing
X Ling, B Bready - US Patent App. 11/538,189, 2007 - Google Patents
A method of employing a nanopore structure in a manner that allows the detection of the
positions (relative and/or absolute) of nucleic acid probes that are hybridized onto a single …
positions (relative and/or absolute) of nucleic acid probes that are hybridized onto a single …
Capture, recapture, and trapping of molecules with a nanopore
MH Gershow, JA Golovchenko, D Branton - US Patent 8,273,532, 2012 - Google Patents
The invention provides nanopore device configurations and techniques for employing such
configurations to enable single molecule manipulation and characterization with a …
configurations to enable single molecule manipulation and characterization with a …
NANO IC packaging
B Tran - US Patent 7,019,391, 2006 - Google Patents
Systems and methods are disclosed to process a semicon ductor substrate by fabricating a
first layer on the substrate using macroscale semiconductor fabrication techniques; …
first layer on the substrate using macroscale semiconductor fabrication techniques; …
Assay methods using nicking endonucleases
JS Oliver - US Patent 8,715,933, 2014 - Google Patents
Assay methods and apparatus for the analysis of biopolymers are disclosed. The assays
employ nicking endonucleases to enable the generation of flaps on target biomolecules …
employ nicking endonucleases to enable the generation of flaps on target biomolecules …