Travelling the world of gene–gene interactions

K Van Steen - Briefings in bioinformatics, 2012 - academic.oup.com
Over the last few years, main effect genetic association analysis has proven to be a
successful tool to unravel genetic risk components to a variety of complex diseases. In the …

BioVLAB-MMIA: a cloud environment for microRNA and mRNA integrated analysis (MMIA) on Amazon EC2

H Lee, Y Yang, H Chae, S Nam, D Choi… - IEEE transactions on …, 2012 - ieeexplore.ieee.org
MicroRNAs, by regulating the expression of hundreds of target genes, play critical roles in
developmental biology and the etiology of numerous diseases, including cancer. As a vast …

Scalable data cube analysis over big data

Z Wang, Y Chu, KL Tan, D Agrawal, AEI Abbadi… - arXiv preprint arXiv …, 2013 - arxiv.org
Data cubes are widely used as a powerful tool to provide multidimensional views in data
warehousing and On-Line Analytical Processing (OLAP). However, with increasing data …

eCEO: an efficient Cloud Epistasis cOmputing model in genome-wide association study

Z Wang, Y Wang, KL Tan, L Wong, D Agrawal - Bioinformatics, 2011 - academic.oup.com
Motivation: Recent studies suggested that a combination of multiple single nucleotide
polymorphisms (SNPs) could have more significant associations with a specific phenotype …

[HTML][HTML] An efficient algorithm to perform multiple testing in epistasis screening

F Van Lishout, JMM John, ES Gusareva… - BMC …, 2013 - ncbi.nlm.nih.gov
Background Research in epistasis or gene-gene interaction detection for human complex
traits has grown over the last few years. It has been marked by promising methodological …

An efficient algorithm to perform multiple testing in epistasis screening

FV Lishout, JM Mahachie John, ES Gusareva… - BMC …, 2013 - Springer
Background Research in epistasis or gene-gene interaction detection for human complex
traits has grown over the last few years. It has been marked by promising methodological …

COSAC: A framework for combinatorial statistical analysis on cloud

Z Wang, D Agrawal, KL Tan - IEEE Transactions on Knowledge …, 2012 - ieeexplore.ieee.org
In many scientific applications, it is critical to determine if there is a relationship between a
combination of objects. The strength of such an association is typically computed using …

Cchi: An efficient cloud epistasis test model in human genome wide association studies

Z Zhou, G Liu, L Su, L Yan, L Han - 2013 6th International …, 2013 - ieeexplore.ieee.org
Due to the vast amounts of SNPs and huge search space, how to decrease the total
computation costs is a challenge in genome wide association studies (GWAS). Triggered by …

BioVLAB-MMIA: a reconfigurable cloud computing environment for microRNA and mRNA integrated analysis

H Lee, Y Yang, H Chae, S Nam, D Choi… - 2011 IEEE …, 2011 - ieeexplore.ieee.org
Micro RNAs, by regulating the expression of hundreds of target genes, play critical roles in
developmental biology and the etiology of numerous diseases, including cancer. As vast …

Scalable Data Analysis on MapReduce-based Systems

W Zhengkui - 2013 - scholarbank.nus.edu.sg
Many of today's applications, such as scientific, financial and social networking applications,
are generating and collecting data at an alarming rate. As the size of data grows, it becomes …