The molecular mechanisms and therapeutic strategies of EMT in tumor progression and metastasis
Y Huang, W Hong, X Wei - Journal of hematology & oncology, 2022 - Springer
Epithelial–mesenchymal transition (EMT) is an essential process in normal embryonic
development and tissue regeneration. However, aberrant reactivation of EMT is associated …
development and tissue regeneration. However, aberrant reactivation of EMT is associated …
Circulating tumor cell isolation for cancer diagnosis and prognosis
Circulating tumor cells (CTCs) are tumor cells that shed from the primary tumor and
intravasate into the peripheral blood circulation system responsible for metastasis. Sensitive …
intravasate into the peripheral blood circulation system responsible for metastasis. Sensitive …
Channel innovations for inertial microfluidics
W Tang, S Zhu, D Jiang, L Zhu, J Yang, N Xiang - Lab on a Chip, 2020 - pubs.rsc.org
Inertial microfluidics has gained significant attention since first being proposed in 2007
owing to the advantages of simplicity, high throughput, precise manipulation, and freedom …
owing to the advantages of simplicity, high throughput, precise manipulation, and freedom …
Inertial microfluidics: current status, challenges, and future opportunities
N Xiang, Z Ni - Lab on a Chip, 2022 - pubs.rsc.org
Inertial microfluidics uses the hydrodynamic effects induced at finite Reynolds numbers to
achieve passive manipulation of particles, cells, or fluids and offers the advantages of high …
achieve passive manipulation of particles, cells, or fluids and offers the advantages of high …
Updates on liquid biopsy: Current trends and future perspectives for clinical application in solid tumors
Despite advances in screening and therapeutics cancer continues to be one of the major
causes of morbidity and mortality worldwide. The molecular profile of tumor is routinely …
causes of morbidity and mortality worldwide. The molecular profile of tumor is routinely …
Orchestration of collective migration and metastasis by tumor cell clusters
A Yamamoto, AE Doak… - Annual Review of …, 2023 - annualreviews.org
Metastatic dissemination has lethal consequences for cancer patients. Accruing evidence
supports the hypothesis that tumor cells can migrate and metastasize as clusters of cells …
supports the hypothesis that tumor cells can migrate and metastasize as clusters of cells …
EMT-associated heterogeneity in circulating tumor cells: sticky friends on the road to metastasis
A Genna, AM Vanwynsberghe, AV Villard, C Pottier… - Cancers, 2020 - mdpi.com
Epithelial–mesenchymal transitions (EMTs) generate hybrid phenotypes with an enhanced
ability to adapt to diverse microenvironments encountered during the metastatic spread …
ability to adapt to diverse microenvironments encountered during the metastatic spread …
Nanoparticle amplification labeling for high-performance magnetic cell sorting
Magnetic cell sorting is an enabling tool for the isolation of specific cellular subpopulations
for downstream applications and requires the cells to be labeled by a sufficient number of …
for downstream applications and requires the cells to be labeled by a sufficient number of …
The role of circulating tumor cells in the metastatic cascade: biology, technical challenges, and clinical relevance
Metastases and cancer recurrence are the main causes of cancer death. Circulating Tumor
Cells (CTCs) and disseminated tumor cells are the drivers of cancer cell dissemination. The …
Cells (CTCs) and disseminated tumor cells are the drivers of cancer cell dissemination. The …
Microfluidic techniques for isolation, formation, and characterization of circulating tumor cells and clusters
Circulating tumor cell (CTC) clusters that are shed from the primary tumor into the
bloodstream are associated with a poor prognosis, elevated metastatic potential, higher …
bloodstream are associated with a poor prognosis, elevated metastatic potential, higher …